Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 7/20 | 0.71 |
| ▸ | NPC1 | O15118 | 6/20 | 0.71 |
| ▸ | L3MBTL1 | Q9Y468 | 6/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 4/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.47 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.44 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.44 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | STAT3 | P40763 | 1/20 | 0.41 |
| ▸ | STAT1 | P42224 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | DRD4 | P21917 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6741453 | 0.86 | RAB9A (0.81) | RAB9ANPC1L3MBTL1SMN1; SMN2TDP1 | |
| SCHEMBL18031153 | 0.85 | RAB9A (0.78) | RAB9ANPC1L3MBTL1SMN1; SMN2TDP1 | |
| SCHEMBL22527378 | 0.79 | RAB9A (0.67) | RAB9ANPC1L3MBTL1SMN1; SMN2TDP1 | |
| SCHEMBL22527377 | 0.78 | RAB9A (0.66) | RAB9ANPC1L3MBTL1SMN1; SMN2TDP1 | |
| SCHEMBL22527380 | 0.77 | RAB9A (0.65) | RAB9ANPC1L3MBTL1SMN1; SMN2TDP1 | |
| SCHEMBL13844529 | 0.77 | RAB9A (0.61) | RAB9ANPC1L3MBTL1SMN1; SMN2TDP1 | |
| SCHEMBL22527379 | 0.76 | RAB9A (0.63) | RAB9ANPC1L3MBTL1SMN1; SMN2TDP1 | |
| SCHEMBL22499759 | 0.76 | RAB9A (0.63) | RAB9ANPC1L3MBTL1SMN1; SMN2TDP1 | |
| SCHEMBL22499758 | 0.76 | RAB9A (0.63) | RAB9ANPC1L3MBTL1SMN1; SMN2TDP1 | |
| SCHEMBL9382780 | 0.75 | RAB9A (0.94) | RAB9ANPC1L3MBTL1SMN1; SMN2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6689771-B2 | TREATMENT OF RHEUMATOID ARTHRITIS, OSTEOARTHRITIS, PERIODONTITIS, GINGIVITIS, CORNEAL ULCERATION, SOLID TUMOR GROWTH | BRISTOL-MYERS SQUIBB PHARMA COMPANY | 2004-02-10 | — | — | US | disclosed |