SCHEMBL674327

SCHEMBL674327

C=CCC(C#N)=CC=Cc1ccccc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MCL1 Q07820 2/20 0.53
LMNA P02545 5/20 0.44
ALDH1A1 P00352 4/20 0.44
MAPT P10636 3/20 0.44
SMN1; SMN2 Q16637 2/20 0.44
HTT P42858 1/20 0.44
KDM4E B2RXH2 1/20 0.44
HPGD P15428 1/20 0.44
KMT2A Q03164 3/20 0.43
MAOB P27338 1/20 0.41
CA12 O43570 1/20 0.40
CA1 P00915 1/20 0.40
CA2 P00918 1/20 0.40
CA9 Q16790 1/20 0.40
GAA P10253 1/20 0.38
APP P05067 2/20 0.37
SNCA P37840 1/20 0.37
MEN1 O00255 2/20 0.36
GRIK1 P39086 1/20 0.36
MAPK1 P28482 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4078927 0.80 MCL1 (0.51) MCL1LMNAALDH1A1MAPTSMN1; SMN2
SCHEMBL7109240 0.80 MCL1 (0.47) MCL1LMNAALDH1A1MAPTSMN1; SMN2
SCHEMBL7214832 0.75 MCL1 (0.47) MCL1LMNAALDH1A1MAPTSMN1; SMN2
SCHEMBL9417087 0.73 MCL1 (0.59) MCL1LMNAALDH1A1MAPTSMN1; SMN2
SCHEMBL6278918 0.73 MCL1 (0.59) MCL1LMNAALDH1A1MAPTSMN1; SMN2
SCHEMBL9467759 0.72 GRIK1 (0.57) MCL1LMNAALDH1A1MAPTSMN1; SMN2
Butadiene SCHEMBL27396222 0.72 MCL1 (0.50) MCL1LMNAALDH1A1MAPTSMN1; SMN2
Allylamine SCHEMBL2214884 0.72 MCL1 (0.65) MCL1LMNAALDH1A1MAPTSMN1; SMN2
Allylamine SCHEMBL2214896 0.72 MCL1 (0.65) MCL1LMNAALDH1A1MAPTSMN1; SMN2
Acrylonitrile SCHEMBL3269498 0.71 MCL1 (0.49) MCL1LMNAALDH1A1MAPTSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3560998-B1 RESIN COMPOSITION AND MOLDED PRODUCT MANUFACTURED THEREFROM LOTTE ADVANCED MAT CO LTD (KR) 2021-06-16 EP claimed
EP-2663592-B1 POLYMER COMPOSITIONS, METHOD OF MANUFACTURE, AND ARTICLES FORMED THEREFROM SABIC INNOVATIVE PLASTICS IP (NL) 2016-06-15 EP claimed
EP-2291454-B1 POLYMER COMPOSITIONS, METHOD OF MANUFACTURE, AND ARTICLES FORMED THEREFROM SABIC GLOBAL TECHNOLOGIES BV (NL) 2016-03-23 EP claimed
US-8067493-B2 Polymer compositions, method of manufacture, and articles formed therefrom SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2011-11-29 US claimed
US-8034866-B2 Polyester, polycarbonate, impact modifier, reinforcing filler, fibrillated fluoropolymer, and antioxidants, mold release agents, colorants, quenchers, or stabilizers; power tool housings; higher modulus, improved ductility, impact strength, melt processability, molding speed; cost efficiency SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2011-10-11 US claimed
EP-2291454-A1 POLYMER COMPOSITIONS, METHOD OF MANUFACTURE, AND ARTICLES FORMED THEREFROM SABIC Innovative Plastics IP B.V. (NL) 2011-03-09 EP claimed
EP-2276809-A1 POLYMER COMPOSITIONS, METHOD OF MANUFACTURE, AND ARTICLES FORMED THEREFROM SABIC Innovative Plastics IP B.V. (NL) 2011-01-26 EP claimed
US-7868090-B2 Polyester molding compositions SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2011-01-11 US claimed
EP-2099863-B1 POLYESTER MOLDING COMPOSITIONS SABIC INNOVATIVE PLASTICS IP (NL) 2010-11-10 EP claimed
WO-2009137627-A1 POLYMER COMPOSITIONS, METHOD OF MANUFACTURE, AND ARTICLES FORMED THEREFROM SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2009-11-12 WO claimed
WO-2009137626-A1 POLYMER COMPOSITIONS, METHOD OF MANUFACTURE, AND ARTICLES FORMED THEREFROM SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2009-11-12 WO claimed
EP-2099863-A1 POLYESTER MOLDING COMPOSITIONS Sabic Innovative Plastics IP B.V. (NL) 2009-09-16 EP claimed
EP-1702006-B1 POLYMER COMPOSITIONS, METHOD OF MANUFACTURE, AND ARTICLES FORMED THEREFROM SABIC INNOVATIVE PLASTICS IP (NL) 2009-06-17 EP claimed
US-20080246181-A1 Polymer Compositions, Method of Manufacture, and Articles Formed Therefrom SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2008-10-09 US claimed
US-20080242789-A1 Polymer Compositions, Method of Manufacture, and Articles Formed Therefrom SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2008-10-02 US claimed
WO-2008082708-A1 POLYESTER MOLDING COMPOSITIONS SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2008-07-10 WO claimed
US-20080161468-A1 mixing a polyester, a fluoropolymer and a carboxy reactive compound such as multifunctional glycidyl compunds,epoxy phenolic novolaks, glycidyl containing silane mono or polymer) effective to form the polyester having at least 20% higher impact strength and tensile elongation; automobile panels, doors SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2008-07-03 US claimed
US-20050143508-A1 Resin compositions with fluoropolymer filler combinations GENERAL ELECTRIC COMPANY 2005-06-30 US claimed
CN-114981345-B Method for forming expanded beads comprising nanostructured fluoropolymer 高新特殊工程塑料全球技术有限公司 2024-03-12 CN disclosed
EP-0739914-A1 Encapsulated tetrafluoroethylene polymerizate-based polymer blends GENERAL ELECTRIC COMPANY (US) 1996-10-30 EP disclosed