Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 1/20 | 0.57 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.46 |
| ▸ | PAM | P19021 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | LMNA | P02545 | 5/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.41 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.41 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5478415 | 0.85 | PAM (0.59) | GRIK1MCL1PAMMAOBALDH1A1 | |
| SCHEMBL11795963 | 0.84 | GRIK1 (0.55) | GRIK1MCL1PAMMAOBALDH1A1 | |
| SCHEMBL9693252 | 0.80 | HAO1 (0.43) | GRIK1PAMMAOBALDH1A1LMNA | |
| Acrylic Acid SCHEMBL5875513 | 0.80 | GRIK1 (0.54) | GRIK1MCL1MAOBALDH1A1LMNA | |
| SCHEMBL221210 | 0.79 | GRIK1 (0.60) | GRIK1MCL1PAMMAOBALDH1A1 | |
| SCHEMBL10334374 | 0.79 | GRIK1 (0.60) | GRIK1MCL1PAMMAOBALDH1A1 | |
| SCHEMBL10394714 | 0.79 | GRIK1 (0.60) | GRIK1MCL1PAMMAOBALDH1A1 | |
| SCHEMBL5597302 | 0.79 | GRIK1 (0.60) | GRIK1MCL1PAMMAOBALDH1A1 | |
| SCHEMBL5031405 | 0.79 | GRIK1 (0.60) | GRIK1MCL1PAMMAOBALDH1A1 | |
| SCHEMBL7064025 | 0.79 | CYP3A4 (0.59) | GRIK1PAMALDH1A1CYP2C9CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5202449-A | Crystallization from acidity solution | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1993-04-13 | — | — | US | disclosed |
| EP-0531637-A1 | Recovery process for antibiotics LL-E19020 alpha and beta | AMERICAN CYANAMID COMPANY (US) | 1993-03-17 | — | — | EP | disclosed |
| US-5188945-A | Fermentation of streptomyces | AMERICAN CYANAMID COMPANY (US) | 1993-02-23 | — | — | US | disclosed |
| US-4918208-A | Process for producing 7-dimethylamino-6-demethyl-6-deoxytetracycline | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1990-04-17 | — | — | US | disclosed |