Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 19/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 6/20 | 0.43 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6741058 | 0.91 | PTGS2 (0.49) | PTGS2PTGS1SCN9A | |
| SCHEMBL6735110 | 0.82 | PTGS2 (0.49) | PTGS2PTGS1SCN9A | |
| SCHEMBL6734626 | 0.82 | SCN9A (0.41) | PTGS2PTGS1SCN9A | |
| SCHEMBL6737139 | 0.81 | PTGS2 (0.38) | PTGS2PTGS1 | |
| SCHEMBL6733271 | 0.81 | PTGS2 (0.46) | PTGS2PTGS1 | |
| SCHEMBL6735005 | 0.79 | PTGS2 (0.38) | PTGS2PTGS1 | |
| SCHEMBL6735172 | 0.78 | PTGS2 (0.46) | PTGS2PTGS1 | |
| SCHEMBL6735812 | 0.78 | PTGS2 (0.46) | PTGS2PTGS1 | |
| SCHEMBL6732652 | 0.78 | PTGS2 (0.45) | PTGS2PTGS1 | |
| SCHEMBL6737306 | 0.78 | PTGS2 (0.41) | PTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6699884-B2 | ANTIINFLAMMATORY CYCLOOXYGENASE INHIBITORS. | PHARMACIA CORPORATION | 2004-03-02 | — | — | US | claimed |