SCHEMBL6743385

SCHEMBL6743385

S=C1OC(COCc2ccccc2)CS1

nearest known ligand 0.54

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.54
TSHR P16473 1/20 0.41
TAAR1 Q96RJ0 1/20 0.40
HRH4 Q9H3N8 4/20 0.40
HRH3 Q9Y5N1 4/20 0.40
PTPN1 P18031 2/20 0.39
CDC25B P30305 1/20 0.39
DRD1 P21728 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.37
BCHE P06276 1/20 0.37
ACHE P22303 1/20 0.37
CTSL P07711 1/20 0.36
CTSB P07858 1/20 0.36
CTSK P43235 1/20 0.36
AKT1 P31749 1/20 0.36
POLB P06746 1/20 0.35
HTT P42858 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4811988 0.78 TDP1 (0.54) TSHRHRH3L3MBTL1
SCHEMBL7004199 0.74 LMNA (0.46) LMNATSHRTAAR1HRH4HRH3
SCHEMBL153049 0.73 LMNA (0.57) LMNATSHRTAAR1HRH4HRH3
SCHEMBL306297 0.73 LMNA (0.57) LMNATSHRTAAR1HRH4HRH3
SCHEMBL715660 0.73 LMNA (0.57) LMNATSHRTAAR1HRH4HRH3
Water SCHEMBL8913477 0.72 LMNA (0.55) LMNATSHRTAAR1HRH4HRH3
SCHEMBL16993434 0.72 LMNA (0.55) LMNATSHRTAAR1HRH4HRH3
Ammonia Solution, Strong SCHEMBL28849284 0.72 LMNA (0.55) LMNATSHRTAAR1HRH4HRH3
SCHEMBL3143177 0.71 LMNA (0.55) LMNATSHRTAAR1HRH4HRH3
SCHEMBL3142790 0.71 LMNA (0.63) LMNATSHRTAAR1HRH4HRH3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6689463-B2 ACRYLATE FUNCTIONAL END GROUP COMPONENT AND A COMPONENT HAVING A HETEROCYCLIC MOIETY CAPABLE OF UNDERGOING RING OPENING POLYMERIZATION; AFTER CURING HAS A YOUNG'S MODULUS OF >/= 100 MPA CORNING INCORPORATED 2004-02-10 US claimed
WO-2003051930-A1 SECONDARY COATING COMPOSITION FOR OPTICAL FIBERS CORNING INCORPORATED (US) 2003-06-26 WO claimed
US-20030113091-A1 Secondary coating composition for optical fibers CORNING INCORPORATED 2003-06-19 US claimed
US-6689463-B2 ACRYLATE FUNCTIONAL END GROUP COMPONENT AND A COMPONENT HAVING A HETEROCYCLIC MOIETY CAPABLE OF UNDERGOING RING OPENING POLYMERIZATION; AFTER CURING HAS A YOUNG'S MODULUS OF >/= 100 MPA CORNING INCORPORATED 2004-02-10 US disclosed
WO-2003051930-A1 SECONDARY COATING COMPOSITION FOR OPTICAL FIBERS CORNING INCORPORATED (US) 2003-06-26 WO disclosed
US-20030113091-A1 Secondary coating composition for optical fibers CORNING INCORPORATED 2003-06-19 US disclosed