⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Chloroprene SCHEMBL10829182 | 0.70 | — | — | |
| Chloroprene SCHEMBL9451156 | 0.67 | ALDH1A1 (0.43) | — | |
| SCHEMBL420701 | 0.67 | — | — | |
| Chloroprene SCHEMBL11408807 | 0.67 | ALDH1A1 (0.43) | — | |
| Chloroprene SCHEMBL20161 | 0.67 | — | — | |
| SCHEMBL1790892 | 0.67 | — | — | |
| Chloroprene SCHEMBL2357094 | 0.65 | ALDH1A1 (0.33) | — | |
| SCHEMBL3114389 | 0.64 | — | — | |
| SCHEMBL222348 | 0.64 | — | — | |
| SCHEMBL22401645 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6541498-B2 | Antiinflammatory agents, antiasthmatics | TEXAS BIOTECHNOLOGY | 2003-04-01 | — | — | US | claimed |
| US-6376523-B1 | HYPOTENSIVE AGENTS; ANTIINFLAMMATORY AGENTS; ENDOGENOUS VASOCONSTRUCTION PEPTIDE | TEXAS BIOTECHNOLOGY CORPORATION | 2002-04-23 | — | — | US | claimed |
| US-20010036958-A1 | Benzenesulfonamides and the use thereof to modulate the activity of endothelin | ENCYSIVE PHARMACEUTICALS, INC. | 2001-11-01 | — | — | US | claimed |
| US-6030991-A | ADJUSTING THE BINDING OF AN ENDOTHELIN PEPTIDE TO ENDOTHELIN A OR, PARTICULARLY, ENDOTHELIN B RECEPTORS, I.E. INHIBITING OR STIMULATING; ANTIINFLAMMATORY AGENT; ASTHMA; KIDNEYS; GASTROINTESTINAL, CARDIOASCULAR DISORDERS; HYPOTENSIVE AGENTS | TEXAS BIOTECHNOLOGY CORP. (US) | 2000-02-29 | — | — | US | claimed |
| US-5514691-A | N-(4-halo-isoxazolyl)-sulfonamides and derivatives thereof that modulate the activity of endothelin | IMMUNOPHARMACEUTICS, INC. (US) | 1996-05-07 | — | — | US | claimed |
| CN-110431457-A | Optical thin film, optical film laminate, polarizing film and image display device | FUJIFILM CORP | 2019-11-08 | — | — | CN | disclosed |
| CN-110312683-A | Silicon-doped metal oxide particles, and ultraviolet absorbing composition containing silicon-doped metal oxide particles | M技术株式会社 | 2019-10-08 | — | — | CN | disclosed |
| CN-107531037-B | laminate | 三菱化学株式会社 | 2019-10-01 | — | — | CN | disclosed |
| CN-109564317-A | Optical thin film, polarizing film and image display device | 富士胶片株式会社 | 2019-04-02 | — | — | CN | disclosed |
| CN-108779207-A | Vinyl chloride polymer composition and process for producing the same | 株式会社LG化学 | 2018-11-09 | — | — | CN | disclosed |
| CN-108368401-A | Rubber-based pressure-sensitive adhesive composition, rubber-based pressure-sensitive adhesive layer, optical film with rubber-based pressure-sensitive adhesive layer, optical member, image display device, and method for producing rubber-based pressure-sensitive adhesive layer | 日东电工株式会社 | 2018-08-03 | — | — | CN | disclosed |
| CN-108369985-A | Antireflection material | 株式会社大赛璐 | 2018-08-03 | — | — | CN | disclosed |
| US-6376523-B1 | HYPOTENSIVE AGENTS; ANTIINFLAMMATORY AGENTS; ENDOGENOUS VASOCONSTRUCTION PEPTIDE | TEXAS BIOTECHNOLOGY CORPORATION | 2002-04-23 | — | — | US | disclosed |
| US-20010036958-A1 | Benzenesulfonamides and the use thereof to modulate the activity of endothelin | ENCYSIVE PHARMACEUTICALS, INC. | 2001-11-01 | — | — | US | disclosed |
| US-6207862-B1 | PRECURSORS ARE CHIRAL 4-HYDROXYCARBOXAMIDES, 4-HYDROXYHYDROXAMIC ACIDS, OR 4-HYDROXYHYDRAZIDES PRODUCED FROM GAMMA-LACTONES, WHICH IN TURN ARE DERIVED FROM 1,4-DIOLS BY STEREOSELECTIVE OXIDATION, | BIOCATALYTICS, INC. | 2001-03-27 | — | — | US | disclosed |
| CN-1051284-C | Coating film transfer tool | SEED RUBBER CO LTD (JP) | 2000-04-12 | — | — | CN | disclosed |
| WO-1999032649-A1 | METHODS AND PRECURSORS FOR THE PRODUCTION OF CHIRAL 1,3-AMINOALCOHOLS | BIOCATALYTICS, INC. (US) | 1999-07-01 | — | — | WO | disclosed |
| US-5916786-A | Method for the production of chiral 1,3-aminoalcohols | BIOCATALYTICS, INC. (US) | 1999-06-29 | — | — | US | disclosed |
| US-5514691-A | N-(4-halo-isoxazolyl)-sulfonamides and derivatives thereof that modulate the activity of endothelin | IMMUNOPHARMACEUTICS, INC. (US) | 1996-05-07 | — | — | US | disclosed |
| US-5464853-A | N-(5-isoxazolyl)biphenylsulfonamides, N-(3-isoxazolyl)biphenylsulfonamides and derivatives thereof that modulate the activity of endothelin | IMMUNOPHARMACEUTICS, INC. (US) | 1995-11-07 | — | — | US | disclosed |