Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP2A | P11388 | 1/20 | 0.40 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 7/20 | 0.37 |
| ▸ | NPC1 | O15118 | 6/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.37 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | KDR | P35968 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | MITF | O75030 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9334583 | 0.81 | NPC1 (0.41) | RAB9ANPC1KDM4EKMT2AMAPT | |
| SCHEMBL18493250 | 0.81 | RAB9A (0.35) | TOP2ATOP2BRAB9ANPC1KDM4E | |
| SCHEMBL7789108 | 0.80 | RAB9A (0.38) | RAB9ANPC1KDM4EKMT2AMAPT | |
| SCHEMBL11799791 | 0.78 | NPC1 (0.36) | RAB9ANPC1KDM4EKMT2AMAPT | |
| SCHEMBL3859298 | 0.76 | NPC1 (0.41) | RAB9ANPC1KDM4EKMT2AMAPT | |
| SCHEMBL3735368 | 0.76 | RAB9A (0.45) | TOP2ATOP2BRAB9ANPC1KDM4E | |
| SCHEMBL7841262 | 0.76 | RAB9A (0.39) | TOP2ATOP2BRAB9ANPC1KDM4E | |
| SCHEMBL7094488 | 0.75 | RAB9A (0.38) | RAB9ANPC1KDM4EKMT2AMAPT | |
| SCHEMBL973209 | 0.75 | IKBKB (0.40) | RAB9ANPC1KDM4EKMT2AMAPT | |
| SCHEMBL7088775 | 0.74 | NPC1 (0.41) | RAB9ANPC1KDM4EKMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040107518-A1 | Hetero-anellated ortho-aminophenols and their use as dye components | CLARIANT FINANCE (BVI) LIMITED (BR) | 2004-06-10 | — | — | US | disclosed |
| EP-1335905-A1 | HETERO-ANELLATED ORTHO-AMINOPHENOLS AND THEIR USE AS DYE COMPONENTS | Clariant International Ltd. (CH) | 2003-08-20 | — | — | EP | disclosed |
| WO-2002038549-A1 | HETERO-ANELLATED ORTHO-AMINOPHENOLS AND THEIR USE AS DYE COMPONENTS | CLARIANT FINANCE (BVI) LTD. (GB) | 2002-05-16 | — | — | WO | disclosed |