Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NISCH | Q9Y2I1 | 8/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | FGB | P02675 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.38 |
| ▸ | TNNT2 | P45379 | 1/20 | 0.38 |
| ▸ | CASP7 | P55210 | 1/20 | 0.38 |
| ▸ | TNNC1 | P63316 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.38 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | RUVBL1 | Q9Y265 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4910323 | 0.82 | NISCH (0.46) | NISCHGAATSHRRUVBL1ADRA2A | |
| Formic Acid SCHEMBL4911274 | 0.80 | NISCH (0.44) | NISCHGAATSHRMEN1FGB | |
| Hydrochloric Acid SCHEMBL4914061 | 0.78 | MC4R (0.46) | NISCHGAATSHRRUVBL1 | |
| SCHEMBL4357405 | 0.77 | MAOB (0.39) | NISCHGAATSHRRUVBL1 | |
| SCHEMBL4360835 | 0.76 | NISCH (0.53) | NISCHMEN1KMT2A | |
| SCHEMBL4160968 | 0.74 | NISCH (0.51) | NISCHGAATSHRKMT2ARUVBL1 | |
| SCHEMBL4070597 | 0.74 | NISCH (0.51) | NISCHMEN1KMT2A | |
| Formic Acid SCHEMBL4912238 | 0.73 | RUVBL1 (0.43) | NISCHGAATSHRRUVBL1MAPT | |
| SCHEMBL1040607 | 0.72 | MAPT (0.58) | NISCHGAAMEN1FGBALOX15 | |
| SCHEMBL31413914 | 0.72 | MAPT (0.58) | NISCHGAAMEN1FGBALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6699873-B1 | EATING DISORDERS | MILLENNIUM PHARMACEUTICALS, INC. | 2004-03-02 | — | — | US | disclosed |