RUVBL1 — patent landscape

Top predicted compounds (top 20 by supporting neighbours, then confidence)

Compound	Confidence	Supporting neighbours
SCHEMBL8252240	0.70	4/20
SCHEMBL9609465	0.68	4/20
SCHEMBL9610738	0.68	4/20
SCHEMBL4523817	0.67	4/20
SCHEMBL6287113	0.66	4/20
SCHEMBL6337317	0.66	4/20
SCHEMBL7035663	0.66	4/20
SCHEMBL11860142	0.65	4/20
SCHEMBL902339	0.63	4/20
SCHEMBL15274740	0.62	4/20
SCHEMBL11751484	0.62	4/20
SCHEMBL11751491	0.62	4/20
SCHEMBL11755973	0.62	4/20
SCHEMBL2988112	0.61	4/20
SCHEMBL15142948	0.60	4/20
SCHEMBL15142954	0.60	4/20
SCHEMBL15142972	0.60	4/20
SCHEMBL902518	0.59	4/20
SCHEMBL7919942	0.59	4/20
SCHEMBL7618815	0.58	4/20

Clinical trials — most relevant to RUVBL1 by text similarity (a relevance ranking, not an exhaustive list)

Trial	Phase	Status
Management of Retinitis Pigmentosa Via Combination of Wharton's Jelly-derived Mesenchymal Stem Cells and Magnovision	PHASE3	COMPLETED
Open Label Study of Everolimus (RAD001) in Patients With Segmental Overgrowth Syndrome	PHASE2	WITHDRAWN
Reverse Transcriptase Inhibitors in AGS	PHASE2	COMPLETED
PS-341 and Radiation to Treat Advanced Cancer of the Head and Neck	PHASE1	COMPLETED
Human Leukocyte Antigen (HLA) - A*2402 Restricted Peptide Vaccine Therapy in Patients With Advanced Gastric Cancer	PHASE1	COMPLETED
New Biomarkers for Diagnosis and Follow-up of Patients With LRBA or CTLA4 Deficiencies	nan	UNKNOWN
Mechanisms of Inherited Retinal Dystrophies Using Whole Genome Sequencing and in Vitro and in Vivo Models	nan	COMPLETED
Prevalence of a Non-Expressing 11B Mutation in Aka Peoples of the Central African Republic	nan	COMPLETED
Diagnosis of RSTS: Identification of the Acetylation Profiles as Epigenetic Markers for Assessing Causality of CREBBP and EP300 Variants.	nan	UNKNOWN
Diagnosis of Inflammatory Bowel Disease	nan	NOT_YET_RECRUITING
Identifying Genes and Mutations Underlying Retinitis Pigmentosa and Allied Diseases	nan	UNKNOWN
Effect of Adenovirus E1A Oncogene on DNA Replication Dynamics	nan	UNKNOWN
Autophagy in Systemic Lupus Erythematosus	nan	UNKNOWN
Exome Analysis in Hearing Impaired Patients	nan	UNKNOWN
Biomarkers in SCOTland CardiomyopatHy Registry (Bio-SCOTCH)	nan	RECRUITING
International PPB/DICER1 Registry	nan	RECRUITING
Study of the Pathophysiological Mechanisms Involved in Bleeding Events	nan	COMPLETED
Dilated Cardiomyopathy-Cardiac Magnetic Resonance (DCM-CMR) Ancillary Study	nan	ACTIVE_NOT_RECRUITING
A Patient-tailored Genetic/Biomarker/iPSC Combined Approach in ALS - PERMEALS	nan	RECRUITING
The Role of FGL2-FcgammaRIIB Inhibitory Pathway in Human Viral Hepatitis	nan	COMPLETED
Multi-Dimensional Genomic Dissection of Ring Chromosome 14 Syndrome	nan	ACTIVE_NOT_RECRUITING
Assessing the Polygenic Burden of Rare Disruptive Mutations in Parkinson's Disease	nan	UNKNOWN
The BRAVE Study- The Identification of Genetic Variants Associated With Bicuspid Aortic Valve Using a Combination of Case-control and Family-based Approaches.	nan	RECRUITING
MiRNA223 and HMGB1 as Apredictos for Drug Resistant Epilepsy	nan	UNKNOWN
Genetic Bases of Neuroendocrine Neoplasms in Mexican Patients	nan	RECRUITING
Investigation of the Genetic Causes of Kallmann Syndrome and Reproductive Disorders	nan	COMPLETED
Identification of Genetic Variants Associated With Unexpected Infant Death Syndrome	nan	RECRUITING
Genetics of Rolandic Epilepsy	nan	COMPLETED
Epidemiologic, Clinical and Molecular Characteristics of Patients With Acute Respiratory Failure Affected by 2019-NCOV.	nan	UNKNOWN
Characterization of New Candidate Genes in Cases of Human Inherited Thrombocytopenia (CATCH)	nan	COMPLETED

Related proteins — ESM-2 sequence neighbours (a RUVBL1 binder may also engage these)

Protein	Name	Similarity
P60123	—	1.000	P60123 →
P60122	—	1.000	P60122 →
Q9VH07	—	1.000	Q9VH07 →
Q9DE26	—	1.000	Q9DE26 →
Q0IFL2	—	1.000	Q0IFL2 →
Q8WZS3	—	1.000	Q8WZS3 →
Q5A0W7	—	1.000	Q5A0W7 →
Q9C0X6	—	1.000	Q9C0X6 →
Q6CB52	—	1.000	Q6CB52 →
Q6CQA9	—	1.000	Q6CQA9 →
Q8AWW7	—	1.000	Q8AWW7 →
Q03940	—	0.999	Q03940 →
Q6FU78	—	0.999	Q6FU78 →
Q5BBV9	—	0.999	Q5BBV9 →
Q5AGZ9	—	0.999	Q5AGZ9 →
Q29AK9	—	0.999	Q29AK9 →
Q4ICA8	—	0.999	Q4ICA8 →
Q9FMR9	—	0.999	Q9FMR9 →
Q755G5	—	0.998	Q755G5 →
Q750R1	—	0.998	Q750R1 →
Q873C7	—	0.997	Q873C7 →
Q6CT29	—	0.997	Q6CT29 →
Q4WPW8	—	0.997	Q4WPW8 →
Q6FSF1	—	0.996	Q6FSF1 →
Q16TA2	—	0.996	Q16TA2 →
Q6BI60	—	0.996	Q6BI60 →
Q5BGK3	—	0.996	Q5BGK3 →
Q6C3X6	—	0.996	Q6C3X6 →
Q9GZH2	—	0.996	Q9GZH2 →
Q4WKH9	—	0.995	Q4WKH9 →