Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 7/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
| ▸ | SHBG | P04278 | 1/20 | 0.32 |
| ▸ | CES2 | O00748 | 1/20 | 0.31 |
| ▸ | CES1 | P23141 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 2/20 | 0.31 |
| ▸ | CA1 | P00915 | 2/20 | 0.31 |
| ▸ | CA2 | P00918 | 2/20 | 0.31 |
| ▸ | MMP2 | P08253 | 2/20 | 0.31 |
| ▸ | CA9 | Q16790 | 2/20 | 0.31 |
| ▸ | DPP4 | P27487 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2867264 | 0.78 | EPHX1 (0.52) | EPHX1ALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL14916107 | 0.78 | EPHX1 (0.52) | EPHX1ALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL479250 | 0.78 | EPHX1 (0.52) | EPHX1ALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL4015606 | 0.78 | EPHX1 (0.44) | EPHX1ALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL4422113 | 0.78 | EPHX1 (0.44) | EPHX1ALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL4957639 | 0.78 | EPHX1 (0.44) | EPHX1ALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL11225412 | 0.77 | EPHX1 (0.48) | EPHX1ALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL6824087 | 0.77 | EPHX1 (0.40) | EPHX1ALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL43523 | 0.76 | EPHX1 (0.48) | EPHX1ALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL1088361 | 0.75 | EPHX1 (0.39) | EPHX1ALDH1A1NPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6695880-B1 | Intraocular lenses and methods for their manufacture | JOHNSON & JOHNSON VISION CARE, INC. | 2004-02-24 | — | — | US | disclosed |
| EP-1333775-A2 | INTRAOCULAR LENSES AND METHODS FOR THEIR MANUFACTURE | Johnson & Johnson Vision Care, Inc. (US) | 2003-08-13 | — | — | EP | disclosed |
| WO-2002034158-A2 | INTRAOCULAR LENSES AND METHODS FOR THEIR MANUFACTURE | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2002-05-02 | — | — | WO | disclosed |