Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGA4 | P13612 | 20/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6742913 | 0.93 | ITGA4 (0.61) | ITGA4 | |
| SCHEMBL6743334 | 0.93 | ITGA4 (0.53) | ITGA4 | |
| SCHEMBL6741334 | 0.90 | ITGA4 (0.46) | ITGA4 | |
| SCHEMBL6743282 | 0.89 | ITGA4 (0.46) | ITGA4 | |
| SCHEMBL6741687 | 0.88 | ITGA4 (0.51) | ITGA4 | |
| SCHEMBL6453971 | 0.85 | ITGA4 (0.62) | ITGA4 | |
| SCHEMBL12166629 | 0.85 | ITGA4 (0.62) | ITGA4 | |
| SCHEMBL12446688 | 0.85 | ITGA4 (0.62) | ITGA4 | |
| SCHEMBL12462209 | 0.85 | ITGA4 (0.62) | ITGA4 | |
| SCHEMBL6743975 | 0.83 | ITGA4 (0.60) | ITGA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6685617-B1 | 4-(((-1-CARBOXY-2-(4-((2,6-DICHLOROBENZOYL)AMINE)PHENYL)ETHYL) AMINO)CARBONYL)-3-OXO-3-THIAZOLIDINEBUTANOIC ACID, USED AS ANTAGONISTS FOR CELLULAR ADHESION MOLECULES, AND ADMINISTERED AS ANTIINFLAMMATORY AGENTS | PHARMACIA & UPJOHN COMPANY | 2004-02-03 | — | — | US | disclosed |
| EP-1089989-A1 | INHIBITORS OF ALPHA4BETA1 MEDIATED CELL ADHESION | PHARMACIA & UPJOHN COMPANY (US) | 2001-04-11 | — | — | EP | disclosed |
| WO-1999067230-A1 | INHIBITORS OF α4β1 MEDIATED CELL ADHESION | PHARMACIA & UPJOHN COMPANY (US) | 1999-12-29 | — | — | WO | disclosed |