Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 18/20 | 0.78 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | HTR1A | P08908 | 1/20 | 0.45 |
| ▸ | DRD2 | P14416 | 1/20 | 0.45 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | HTR7 | P34969 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6741078 | 0.96 | HTR6 (0.80) | HTR6ALDH1A1MAPTHTR1ADRD2 | |
| Hydrochloric Acid SCHEMBL6742041 | 0.95 | HTR6 (0.79) | HTR6ALDH1A1MAPTHTR1ADRD2 | |
| SCHEMBL6745003 | 0.92 | HTR6 (0.71) | HTR6ALDH1A1MAPTHTR1ADRD2 | |
| SCHEMBL6744551 | 0.90 | HTR6 (0.76) | HTR6ALDH1A1MAPT | |
| SCHEMBL6747341 | 0.88 | HTR6 (0.61) | HTR6DRD2HTR2AHTR7 | |
| SCHEMBL6746185 | 0.88 | HTR6 (0.78) | HTR6ALDH1A1MAPTHTR1ADRD2 | |
| SCHEMBL7044626 | 0.88 | HTR6 (0.80) | HTR6ALDH1A1MAPT | |
| SCHEMBL6741906 | 0.88 | HTR6 (0.92) | HTR6MAPTHTR1ADRD2HTR2A | |
| SCHEMBL6743830 | 0.88 | HTR6 (1.00) | HTR6ALDH1A1MAPT | |
| SCHEMBL6746870 | 0.87 | HTR6 (0.70) | HTR6ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040014966-A1 | Bis-arylsulfones | JACOBSEN ERIC JON (US) | 2004-01-22 | — | — | US | claimed |
| US-20040014966-A1 | Bis-arylsulfones | JACOBSEN ERIC JON (US) | 2004-01-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040014966-A1 | Bis-arylsulfones | NPSR1, ARSA, SLC18A2 | HTR6 69/4885ALDH1A1 1243/4885MAPT 1505/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.