SCHEMBL6743744

SCHEMBL6743744

NC(c1ccccc1)(c1ccccc1)[C@H](O)c1ccccc1

nearest known ligand 0.47

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
AOC3 Q16853 2/20 0.47
KCNN4 O15554 1/20 0.44
LMNA P02545 4/20 0.40
ADRA2A P08913 1/20 0.40
ADRA2C P18825 1/20 0.40
HIF1A Q16665 1/20 0.40
KDM4E B2RXH2 1/20 0.40
CYP1A2 P05177 1/20 0.39
CYP2D6 P10635 1/20 0.39
ALDH1A1 P00352 1/20 0.39
CES2 O00748 1/20 0.39
CES1 P23141 1/20 0.39
DPP4 P27487 2/20 0.39
F2 P00734 1/20 0.39
MAPK1 P28482 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9029040 0.82 AOC3 (0.47) AOC3KCNN4LMNAADRA2AADRA2C
SCHEMBL14297806 0.82 KIF11 (0.43) AOC3LMNACYP2D6
SCHEMBL10451736 0.78 AOC3 (0.53) AOC3KCNN4LMNAADRA2AADRA2C
SCHEMBL8325119 0.77 AOC3 (0.47) AOC3KCNN4LMNAADRA2AADRA2C
SCHEMBL8674747 0.76 AOC3 (0.45) AOC3LMNAADRA2AADRA2CHIF1A
SCHEMBL11133940 0.76 CYP2D6 (0.52) KCNN4LMNAADRA2AADRA2CHIF1A
SCHEMBL5463176 0.76 AOC3 (0.50) AOC3LMNAADRA2AADRA2CHIF1A
SCHEMBL759901 0.76 KIF11 (0.48)
SCHEMBL411887 0.74 AOC3 (0.59) AOC3LMNAADRA2AADRA2CHIF1A
SCHEMBL1905925 0.74 AOC3 (0.44) AOC3LMNAADRA2AADRA2CHIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1213293-B1 Use of chiral, uncharged metal compounds as doting agents for liquid crystals BASF AG (DE) 2004-06-23 EP disclosed
US-6695977-B2 LIQUID CRYSTALLINE MIXTURE BASF AKTIENGESELLSCHAFT (DE) 2004-02-24 US disclosed
US-20030066984-A1 Use of chiral, uncharged metal compounds as dopants for liquid-crystalline materials BASF AKTIENGESELLSCHAFT (DE) 2003-04-10 US disclosed
EP-1213293-A1 Use of chiral, uncharged metal compounds as doting agents for liquid crystals BASF AKTIENGESELLSCHAFT (DE) 2002-06-12 EP disclosed