Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.37 |
| ▸ | CDK1 | P06493 | 1/20 | 0.37 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.37 |
| ▸ | GSK3A | P49840 | 1/20 | 0.37 |
| ▸ | GSK3B | P49841 | 1/20 | 0.37 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.37 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.36 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.36 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | HRH1 | P35367 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 5/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20873451 | 0.98 | CCNB2 (0.39) | CYP2D6TDP1L3MBTL1CYP3A4CCNB2 | |
| SCHEMBL997911 | 0.94 | CYP2D6 (0.39) | CYP2D6TDP1L3MBTL1CYP3A4CCNB2 | |
| SCHEMBL2581673 | 0.86 | CYP2D6 (0.37) | CYP2D6CCNB2CDK1CCNB1GSK3A | |
| SCHEMBL28229981 | 0.82 | CCNB2 (0.36) | CYP2D6CCNB2CDK1CCNB1GSK3A | |
| SCHEMBL1074604 | 0.81 | TDP1 (0.47) | CYP2D6TDP1L3MBTL1CYP3A4PTGS2 | |
| SCHEMBL27818098 | 0.79 | TDP1 (0.45) | TDP1L3MBTL1CYP3A4PTGS2CHRM1 | |
| SCHEMBL2585189 | 0.78 | CYP2D6 (0.39) | CYP2D6TDP1L3MBTL1CYP3A4CYP19A1 | |
| SCHEMBL30149469 | 0.78 | CYP2D6 (0.33) | CYP2D6CHRM1HRH1KCNH2CYP19A1 | |
| SCHEMBL5175641 | 0.78 | CYP2D6 (0.33) | CYP2D6CHRM1HRH1KCNH2CYP19A1 | |
| SCHEMBL30610260 | 0.77 | CYP2D6 (0.35) | CYP2D6PTGS2CHRM1HRH1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150190504-A1 | WOUND HEALING | KINETIC CONCEPTS, INC. | 2015-07-09 | — | — | US | disclosed |
| US-8957076-B2 | Wound healing | SYSTAGENIX WOUND MANAGEMENT (US), INC. (US) | 2015-02-17 | — | — | US | disclosed |
| US-8063052-B2 | Wound healing | SYSTAGENIX WOUND MANAGEMENT (US), INC. (US) | 2011-11-22 | — | — | US | disclosed |
| US-20100099622-A1 | WOUND HEALING | SYSTAGENIX WOUND MANAGEMENT (US), INC. (US) | 2010-04-22 | — | — | US | disclosed |
| US-20090170910-A1 | WOUND HEALING | KCI USA, INC. | 2009-07-02 | — | — | US | disclosed |
| EP-1786409-A1 | WOUND HEALING | ETHICON, INC. (US) | 2007-05-23 | — | — | EP | disclosed |
| WO-2006028836-A1 | WOUND HEALING | ETHICON, INC. (US) | 2006-03-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100099622-A1 | WOUND HEALING | MAPK1, MAPK3, MAPK4 | CYP2D6 3746/4885TDP1 2393/4885L3MBTL1 1482/4885 |
| US-20090170910-A1 | WOUND HEALING | MAPK1, MAPK3, MAPK4 | CYP2D6 3746/4885TDP1 2393/4885L3MBTL1 1482/4885 |
| US-20150190504-A1 | WOUND HEALING | MAPK1, MAPK3, MAPK4 | CYP2D6 3746/4885TDP1 2393/4885L3MBTL1 1482/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.