SCHEMBL2581673

SCHEMBL2581673

CCCc1nccnc1OC

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2D6 P10635 3/20 0.37
HRH1 P35367 3/20 0.37
CHRM1 P11229 2/20 0.37
KCNH2 Q12809 2/20 0.37
PDE3B Q13370 1/20 0.35
PDE3A Q14432 1/20 0.35
CCNB2 O95067 1/20 0.33
CDK1 P06493 1/20 0.33
CCNB1 P14635 1/20 0.33
GSK3A P49840 1/20 0.33
GSK3B P49841 1/20 0.33
CDK5 Q00535 1/20 0.33
CDK5R1 Q15078 1/20 0.33
CCNB3 Q8WWL7 1/20 0.33
CRHR1 P34998 1/20 0.31
PDE10A Q9Y233 2/20 0.31
APLNR P35414 1/20 0.31
SLC6A2 P23975 1/20 0.31
SLC6A4 P31645 1/20 0.31
HMGCR P04035 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL997911 0.88 CYP2D6 (0.39) CYP2D6HRH1CHRM1KCNH2CCNB2
SCHEMBL674404 0.86 CYP2D6 (0.38) CYP2D6HRH1CHRM1KCNH2CCNB2
SCHEMBL20873451 0.84 CCNB2 (0.39) CYP2D6KCNH2CCNB2CDK1CCNB1
SCHEMBL2586207 0.83 SMN1; SMN2 (0.41) PDE3BPDE3ASLC6A2SLC6A4ALDH1A1
SCHEMBL1607631 0.82 CYP2D6 (0.35) CYP2D6HRH1CHRM1KCNH2PDE3B
SCHEMBL30610260 0.82 CYP2D6 (0.35) CYP2D6HRH1CHRM1KCNH2PDE3B
SCHEMBL28229981 0.79 CCNB2 (0.36) CYP2D6HRH1CHRM1KCNH2CCNB2
SCHEMBL9797792 0.78 PDE3B (0.42) PDE3BPDE3ACCNB2CDK1CCNB1
SCHEMBL15633445 0.77 ALDH1A1 (0.40) CYP2D6HRH1CHRM1KCNH2PDE3B
SCHEMBL29606513 0.77 ALDH1A1 (0.40) CYP2D6HRH1CHRM1KCNH2PDE3B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4125427-A1 FLAVOR COMPOSITION Firmenich SA (CH) 2023-02-08 EP claimed
WO-2021198199-A1 FLAVOR COMPOSITION FIRMENICH SA (CH) 2021-10-07 WO claimed
EP-4125427-A1 FLAVOR COMPOSITION Firmenich SA (CH) 2023-02-08 EP disclosed
WO-2021198199-A1 FLAVOR COMPOSITION FIRMENICH SA (CH) 2021-10-07 WO disclosed
CN-109549167-A Ginseng essence 浙江绿晶香精有限公司 2019-04-02 CN disclosed
US-8052959-B2 Hydrogen supply device and method of supplying hydrogen TOYOTA JIDOSHA KABUSHIKI KAISHA (JP) 2011-11-08 US disclosed
US-20100163802-A1 HYDROGEN SUPPLY DEVICE AND METHOD OF SUPPLYING HYDROGEN TOYOTA JIDOSHA KABUSHIKI KAISHA (JP) 2010-07-01 US disclosed
WO-2004024853-A1 ALKOXY PYRAZINES FOR ODORISING GAS SYMRISE GMBH & CO. KG (DE) 2004-03-25 WO disclosed