Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | ERN1 | O75460 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | TTR | P02766 | 2/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL276717 | 0.91 | HTT (0.60) | HTTPKMTDP1SMN1; SMN2LMNA | |
| SCHEMBL31139772 | 0.91 | HTT (0.60) | HTTPKMTDP1SMN1; SMN2LMNA | |
| SCHEMBL9876067 | 0.90 | HTT (0.53) | HTTPKMTDP1SMN1; SMN2LMNA | |
| Hydrochloric Acid SCHEMBL8501645 | 0.90 | HTT (0.58) | HTTPKMTDP1SMN1; SMN2LMNA | |
| Hydrochloric Acid SCHEMBL10955241 | 0.88 | HTT (0.57) | HTTPKMTDP1SMN1; SMN2LMNA | |
| Hydrochloric Acid SCHEMBL11387243 | 0.88 | HTT (0.57) | HTTPKMTDP1SMN1; SMN2LMNA | |
| Hydrochloric Acid SCHEMBL10949926 | 0.87 | HTT (0.55) | HTTPKMTDP1SMN1; SMN2LMNA | |
| SCHEMBL10836987 | 0.86 | HTT (0.54) | HTTPKMTDP1SMN1; SMN2LMNA | |
| SCHEMBL4606843 | 0.86 | HTT (0.54) | HTTPKMTDP1SMN1; SMN2LMNA | |
| SCHEMBL6744048 | 0.80 | HTT (0.48) | HTTPKMTDP1SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6696297-B2 | DETECTING BILIRUBIN IN A SAMPLE TO OBTAIN A FIRST MEASUREMENT INDICATIVE OF AMOUNT OF BILIRUBIN IN SAMPLE; DETECTING BILIRUBIN ANALOG COMPOUND IN CONTROL REAGENT TO OBTAIN MEASUREMENT INDICATIVE OF AMOUNT OF ANALOG; COMPARING | MEDICAL ANALYSIS SYSTEMS, INC. | 2004-02-24 | — | — | US | disclosed |
| US-20020146630-A1 | Non-oxidizable bilirubin substitutes and uses therefor | MEDICAL ANALYSIS SYSTEMS, INC. | 2002-10-10 | — | — | US | disclosed |