Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.44 |
| ▸ | ALPL | P05186 | 1/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11387243 | 0.98 | HTT (0.57) | HTTTDP1LMNASMN1; SMN2PKM | |
| Hydrochloric Acid SCHEMBL10955241 | 0.98 | HTT (0.57) | HTTTDP1LMNASMN1; SMN2PKM | |
| SCHEMBL276717 | 0.98 | HTT (0.60) | HTTTDP1LMNASMN1; SMN2PKM | |
| SCHEMBL31139772 | 0.98 | HTT (0.60) | HTTTDP1LMNASMN1; SMN2PKM | |
| Hydrochloric Acid SCHEMBL10949926 | 0.97 | HTT (0.55) | HTTTDP1LMNASMN1; SMN2PKM | |
| SCHEMBL4606843 | 0.92 | HTT (0.54) | HTTTDP1LMNASMN1; SMN2PKM | |
| SCHEMBL10836987 | 0.92 | HTT (0.54) | HTTTDP1LMNASMN1; SMN2PKM | |
| SCHEMBL9876067 | 0.91 | HTT (0.53) | HTTTDP1LMNASMN1; SMN2PKM | |
| Boric Acid SCHEMBL6744053 | 0.90 | HTT (0.51) | HTTTDP1LMNASMN1; SMN2PKM | |
| SCHEMBL6744048 | 0.86 | HTT (0.48) | HTTTDP1LMNASMN1; SMN2PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9759733-B1 | Mass produced, low cost, portable test kit for the detection and identification of narcotics | VERITEQUE USA, INC. | 2017-09-12 | — | — | US | claimed |
| US-9759733-B1 | Mass produced, low cost, portable test kit for the detection and identification of narcotics | VERITEQUE USA, INC. | 2017-09-12 | — | — | US | disclosed |
| EP-0599270-B1 | Method of detecting phosphatase | AISIN SEIKI (JP) | 1999-05-12 | — | — | EP | disclosed |
| US-5480791-A | Method of detecting phosphatase | AISIN SEIKI KABUSHIKI KAISHA (JP) | 1996-01-02 | — | — | US | disclosed |
| EP-0599270-A2 | Method of detecting phosphatase | AISIN SEIKI KABUSHIKI KAISHA (JP) | 1994-06-01 | — | — | EP | disclosed |
| EP-0297583-A2 | Photosensitive material and image forming method by use thereof | CANON KABUSHIKI KAISHA (JP) | 1989-01-04 | — | — | EP | disclosed |
| EP-0254000-A1 | Rapid detection of N. gonorrhoeae without culture | MILES INC. (US) | 1988-01-27 | — | — | EP | disclosed |