SCHEMBL6744326

SCHEMBL6744326

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nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
GBA1 P04062 1/20 0.32
CYP3A4 P08684 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18335379 1.00 GBA1 (0.32) GBA1CYP3A4
SCHEMBL18335378 0.97 GBA1 (0.35) GBA1
SCHEMBL18335397 0.95 CYP3A4 (0.30) CYP3A4
SCHEMBL18335407 0.95 GBA1 (0.37) GBA1CYP3A4
SCHEMBL4374229 0.90 SLC2A1 (0.33) GBA1CYP3A4
SCHEMBL13528521 0.86 SLC2A1 (0.33) CYP3A4
SCHEMBL17131873 0.86 SLC2A1 (0.33) CYP3A4
SCHEMBL827322 0.86 ALDH1A1 (0.35) CYP3A4
SCHEMBL9439413 0.78 BCHE (0.52) CYP3A4
SCHEMBL9293835 0.78 BCHE (0.52) CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109689634-A The manufacturing method of polynary glycidyl compound 昭和电工株式会社 2019-04-26 CN disclosed
US-20040131551-A1 Enhanced relaxivity monomeric and multimeric compounds BRISTOL-MYERS SQUIBB COMPANY 2004-07-08 US disclosed
US-6693190-B1 TETRAAZACYCLODODECANE MACROCYCLE DERIVATIVES INCLUDING METAL COMPLEXES; MAGNETIC RESONANCE IMAGING AGENTS BRACCO INTERNATIONAL B.V. (NL) 2004-02-17 US disclosed
EP-0708761-B1 ENHANCED RELAXIVITY MONOMERIC AND MULTIMERIC COMPOUNDS BRACCO INT BV (NL) 2002-08-14 EP disclosed
WO-1995031444-A1 ENHANCED RELAXIVITY MONOMERIC AND MULTIMERIC COMPOUNDS BRACCO INTERNATIONAL B.V. (NL) 1995-11-23 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040131551-A1 Enhanced relaxivity monomeric and multimeric compounds H1-2, H1-0, H1-3 GBA1 2439/4885CYP3A4 3246/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.