Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 5/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | NR2F2 | P24468 | 2/20 | 0.34 |
| ▸ | GALR3 | O60755 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | MPO | P05164 | 1/20 | 0.33 |
| ▸ | TTR | P02766 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.32 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6760580 | 0.78 | SMN1; SMN2 (0.44) | SMN1; SMN2ALDH1A1KDM4ELMNARAB9A | |
| SCHEMBL5898273 | 0.76 | SMN1; SMN2 (0.43) | SMN1; SMN2ALDH1A1KDM4ELMNARAB9A | |
| SCHEMBL5898267 | 0.76 | SMN1; SMN2 (0.47) | SMN1; SMN2ALDH1A1KDM4ELMNARAB9A | |
| SCHEMBL7993567 | 0.76 | SMN1; SMN2 (0.43) | SMN1; SMN2ALDH1A1KDM4ELMNARAB9A | |
| SCHEMBL762264 | 0.76 | SMN1; SMN2 (0.43) | SMN1; SMN2ALDH1A1KDM4ELMNARAB9A | |
| SCHEMBL12844283 | 0.74 | SMN1; SMN2 (0.42) | SMN1; SMN2ALDH1A1KDM4ELMNARAB9A | |
| Hydrochloric Acid SCHEMBL14696281 | 0.74 | ALDH1A1 (0.42) | SMN1; SMN2ALDH1A1KDM4ELMNARAB9A | |
| Hydrochloric Acid SCHEMBL5010811 | 0.74 | ALDH1A1 (0.42) | SMN1; SMN2ALDH1A1KDM4ELMNARAB9A | |
| SCHEMBL23978357 | 0.73 | ALDH1A1 (0.41) | SMN1; SMN2ALDH1A1KDM4ELMNARAB9A | |
| SCHEMBL12926028 | 0.73 | SMN1; SMN2 (0.41) | SMN1; SMN2ALDH1A1KDM4ELMNARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6689771-B2 | TREATMENT OF RHEUMATOID ARTHRITIS, OSTEOARTHRITIS, PERIODONTITIS, GINGIVITIS, CORNEAL ULCERATION, SOLID TUMOR GROWTH | BRISTOL-MYERS SQUIBB PHARMA COMPANY | 2004-02-10 | — | — | US | disclosed |
| US-6376665-B1 | ANTIARTHRITIC AGENTS, ANTIINFLAMMATORY AGENTS | BRISTOL-MYERS SQUIBB PHARMA COMPANY | 2002-04-23 | — | — | US | disclosed |