Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 2/20 | 0.46 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MME | P08473 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CPA1 | P15085 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | CPB1 | P15086 | 1/20 | 0.38 |
| ▸ | CPA3 | P15088 | 1/20 | 0.38 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.38 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.38 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27543712 | 0.92 | TDP1 (0.43) | FOLH1SLC22A6TDP1SMN1; SMN2LMNA | |
| SCHEMBL6844224 | 0.86 | USP2 (0.42) | FOLH1SLC22A6TDP1SMN1; SMN2LMNA | |
| SCHEMBL9270192 | 0.86 | MME (0.44) | FOLH1SLC22A6TDP1SMN1; SMN2LMNA | |
| SCHEMBL22472016 | 0.84 | USP2 (0.41) | FOLH1SLC22A6TDP1SMN1; SMN2LMNA | |
| SCHEMBL22472002 | 0.84 | USP2 (0.41) | FOLH1SLC22A6TDP1SMN1; SMN2LMNA | |
| SCHEMBL4170332 | 0.82 | CHRM1 (0.54) | FOLH1TDP1 | |
| SCHEMBL10000266 | 0.82 | MME (0.55) | FOLH1TDP1MMECPA1 | |
| SCHEMBL25401621 | 0.81 | FOLH1 (0.46) | FOLH1SLC22A6TDP1SMN1; SMN2LMNA | |
| SCHEMBL8532702 | 0.80 | FOLH1 (0.37) | FOLH1SLC22A6TDP1SMN1; SMN2LMNA | |
| SCHEMBL15080402 | 0.80 | SLC1A3 (0.44) | FOLH1SLC22A6TDP1MME |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040086949-A1 | Method for preparing a ligand presenting assembly (LPA), an LPA and uses thereof | STATENS SERUM INSTITUT | 2004-05-06 | — | — | US | claimed |
| EP-1117677-B1 | LIGAND PRESENTING ASSEMBLY (LPA), METHOD OF PREPARATION AND USES THEREOF | STATENS SERUMINSTITUT (DK) | 2003-11-12 | — | — | EP | claimed |
| EP-1117677-A1 | LIGAND PRESENTING ASSEMBLY (LPA), METHOD OF PREPARATION AND USES THEREOF | Statens Serum Institut (DK) | 2001-07-25 | — | — | EP | claimed |
| WO-2000018791-A1 | LIGAND PRESENTING ASSEMBLY (LPA), METHOD OF PREPARATION AND USES THEREOF | STATENS SERUM INSTITUT (DK) | 2000-04-06 | — | — | WO | claimed |
| CN-101027319-A | Heparin binding peptide | ENKAM PHARMACEUTICALS AS (DK) | 2007-08-29 | — | — | CN | disclosed |
| CN-101027320-A | FGFR binding peptides | ENKAM PHARMACEUTICALS AS (DK) | 2007-08-29 | — | — | CN | disclosed |
| CN-1863820-A | Compounds comprising lpa | ENKAM PHARMACEUTICALS AS (DK) | 2006-11-15 | — | — | CN | disclosed |
| US-20040086949-A1 | Method for preparing a ligand presenting assembly (LPA), an LPA and uses thereof | STATENS SERUM INSTITUT | 2004-05-06 | — | — | US | disclosed |
| EP-1117677-B1 | LIGAND PRESENTING ASSEMBLY (LPA), METHOD OF PREPARATION AND USES THEREOF | STATENS SERUMINSTITUT (DK) | 2003-11-12 | — | — | EP | disclosed |
| EP-1117677-A1 | LIGAND PRESENTING ASSEMBLY (LPA), METHOD OF PREPARATION AND USES THEREOF | Statens Serum Institut (DK) | 2001-07-25 | — | — | EP | disclosed |
| WO-2000018791-A1 | LIGAND PRESENTING ASSEMBLY (LPA), METHOD OF PREPARATION AND USES THEREOF | STATENS SERUM INSTITUT (DK) | 2000-04-06 | — | — | WO | disclosed |
| US-4883857-A | Production of photodegradable polyester plastics | ECOPLASTICS LIMITED (CA) | 1989-11-28 | — | — | US | disclosed |
| WO-1989002903-A1 | PRODUCTION OF PHOTODEGRADABLE POLYESTER PLASTICS | ECOPLASTICS LIMITED (CA) | 1989-04-06 | — | — | WO | disclosed |
| US-4066667-A | 9-Hydroxy-7,8,9,10-tetrahydro-6H, dibenzo[b][d] pyrans and pyranones | ABBOTT LABORATORIES (US) | 1978-01-03 | — | — | US | disclosed |