Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.41 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | MME | P08473 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CPA1 | P15085 | 2/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | CPB1 | P15086 | 1/20 | 0.34 |
| ▸ | CPA3 | P15088 | 1/20 | 0.34 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.34 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6744485 | 0.92 | FOLH1 (0.46) | TDP1FOLH1SLC22A6LMNASMN1; SMN2 | |
| SCHEMBL2439880 | 0.89 | ALDH1A1 (0.53) | TDP1ALDH1A1LMNASLC15A2 | |
| SCHEMBL6652778 | 0.84 | FOLH1 (0.52) | TDP1ALDH1A1FOLH1SLC22A6LMNA | |
| SCHEMBL6844224 | 0.79 | USP2 (0.42) | TDP1FOLH1SLC22A6LMNASMN1; SMN2 | |
| SCHEMBL9270192 | 0.79 | MME (0.44) | TDP1FOLH1SLC22A6LMNASMN1; SMN2 | |
| SCHEMBL22472016 | 0.77 | USP2 (0.41) | TDP1FOLH1SLC22A6LMNASMN1; SMN2 | |
| SCHEMBL22472002 | 0.77 | USP2 (0.41) | TDP1FOLH1SLC22A6LMNASMN1; SMN2 | |
| SCHEMBL11305374 | 0.77 | KMT2A (0.47) | TDP1ALDH1A1FOLH1SLC22A6SMN1; SMN2 | |
| SCHEMBL8679924 | 0.76 | ALDH1A1 (0.46) | TDP1ALDH1A1 | |
| SCHEMBL14725173 | 0.76 | ALDH1A1 (0.46) | TDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1251098-A | Pyrrole compounds, their prodn. and their use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2000-04-19 | — | — | CN | disclosed |