SCHEMBL6744558

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4649906	0.87	ALDH1A1 (0.71)	ALDH1A1POLBKMT2APARP10HPGD
	SCHEMBL1652968	0.83	ALDH1A1 (0.59)	ALDH1A1POLBKMT2AHPGDMAOB
	SCHEMBL13263811	0.79	ALDH1A1 (0.59)	ALDH1A1POLBKMT2APARP10HPGD
	SCHEMBL7646688	0.79	ALDH1A1 (0.59)	ALDH1A1POLBKMT2APARP10HPGD
	SCHEMBL3988817	0.79	KDM4E (0.57)	ALDH1A1KMT2APARP10MAOAMAOB
	SCHEMBL9256790	0.78	ALDH1A1 (0.47)	ALDH1A1POLBKMT2APARP10HPGD
	SCHEMBL13265124	0.78	ALDH1A1 (0.58)	ALDH1A1POLBKMT2APARP10HPGD
	SCHEMBL31617906	0.77	ALDH1A1 (0.47)	ALDH1A1POLBKMT2APARP10HPGD
	SCHEMBL16481265	0.76	ALDH1A1 (0.46)	ALDH1A1POLBKMT2APARP10HPGD
	SCHEMBL7657654	0.76	MAOB (0.47)	KMT2AMAOAMAOBMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.