SCHEMBL6744607

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL6745414	0.85	PDE5A (0.39)	LMNATRPA1CHRM1SLC6A2ADRA1A
	SCHEMBL6741699	0.85	PDE5A (0.39)	LMNATRPA1CHRM1SLC6A2ADRA1A
	SCHEMBL6055146	0.80	PDE2A (0.43)	PDE2ALMNATRPA1CHRM1SLC6A2
	SCHEMBL20342536	0.80	PDE2A (0.43)	PDE2ALMNATRPA1CHRM1SLC6A2
	SCHEMBL1343789	0.79	PDE2A (0.47)	PDE2ALMNARAB9ANPC1
	SCHEMBL6744805	0.79	KCNH2 (0.43)	PDE2ALMNATDP1ALDH1A1KDM4E
	SCHEMBL11138508	0.78	LMNA (0.59)	PDE2ALMNATRPA1CHRM1SLC6A2
	SCHEMBL28493300	0.78	LMNA (0.47)	PDE2ALMNATRPA1CHRM1SLC6A2
	SCHEMBL2474757	0.78	LMNA (0.47)	PDE2ALMNATRPA1CHRM1SLC6A2
	SCHEMBL11457242	0.77	LMNA (0.52)	PDE2ALMNATRPA1CHRM1SLC6A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.