Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | MET | P08581 | 3/20 | 0.39 |
| ▸ | KDR | P35968 | 3/20 | 0.38 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.38 |
| ▸ | FEN1 | P39748 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | BRAF | P15056 | 1/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.36 |
| ▸ | TNNI3K | Q59H18 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | FLT1 | P17948 | 1/20 | 0.36 |
| ▸ | FLT4 | P35916 | 1/20 | 0.36 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.35 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6744799 | 1.00 | MEN1 (0.40) | MEN1KMT2AMETKDRALOX5AP | |
| SCHEMBL16561719 | 0.92 | MEN1 (0.41) | MEN1KMT2AKDRNPC1ALDH1A1 | |
| SCHEMBL6743925 | 0.87 | MEN1 (0.39) | MEN1KMT2AKDRNPC1ALDH1A1 | |
| SCHEMBL31493947 | 0.87 | SMN1; SMN2 (0.42) | MEN1KMT2AKDRNPC1ALDH1A1 | |
| SCHEMBL29657093 | 0.87 | SMN1; SMN2 (0.42) | MEN1KMT2AKDRNPC1ALDH1A1 | |
| SCHEMBL6743924 | 0.87 | MEN1 (0.39) | MEN1KMT2AKDRNPC1ALDH1A1 | |
| SCHEMBL709624 | 0.87 | SMN1; SMN2 (0.42) | MEN1KMT2AKDRNPC1ALDH1A1 | |
| SCHEMBL2996165 | 0.87 | SMN1; SMN2 (0.42) | MEN1KMT2AKDRNPC1ALDH1A1 | |
| SCHEMBL22057053 | 0.87 | MEN1 (0.39) | MEN1KMT2AKDRNPC1ALDH1A1 | |
| SCHEMBL9121807 | 0.87 | HTT (0.44) | MEN1KMT2AKDRNPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6777412-B2 | PYRIMIDIN-4-YLOXY)PHENYL)-3-METHOXYPROPENOATE DERIVATIVES | SYNGENTA LIMITED (GB) | 2004-08-17 | — | — | US | disclosed |
| US-20040092746-A1 | Pyrimidinyloxyphenyl-3-alkoxypropenoate derivatives as pesticides | CLOUGH JOHN MARTIN (GB) | 2004-05-13 | — | — | US | disclosed |
| US-6613773-B2 | Pyrimidinyloxyphenyl-3-alkoxypropenoates derivatives | SYNGENTA LIMITED (GB) | 2003-09-02 | — | — | US | disclosed |
| US-20030060626-A1 | Fungicides | SYNGENTA LIMITED (GB) | 2003-03-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040092746-A1 | Pyrimidinyloxyphenyl-3-alkoxypropenoate derivatives as pesticides | DDT, SQOR, TH | MEN1 2186/4885KMT2A 491/4885MET 1416/4885 |
| US-20030060626-A1 | Fungicides | CYP51A1, CYP1A1, CYP1A2 | MEN1 686/4885KMT2A 352/4885MET 1261/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.