Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 4/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.51 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.51 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.51 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.51 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.46 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.43 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 4/20 | 0.42 |
| ▸ | CA2 | P00918 | 4/20 | 0.42 |
| ▸ | IDO1 | P14902 | 2/20 | 0.42 |
| ▸ | CA9 | Q16790 | 3/20 | 0.41 |
| ▸ | MPO | P05164 | 1/20 | 0.41 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL231791 | 0.83 | HSPA5 (0.50) | CYP2D6SLC6A2SLC6A4SLC6A3HSPA5 | |
| SCHEMBL29611994 | 0.83 | HSPA5 (0.50) | CYP2D6SLC6A2SLC6A4SLC6A3HSPA5 | |
| SCHEMBL188373 | 0.79 | TSHR (0.64) | CYP2D6CYP3A4SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL30455902 | 0.79 | TSHR (0.64) | CYP2D6CYP3A4SLC6A2SLC6A4SLC6A3 | |
| Bromide SCHEMBL4863237 | 0.78 | HSPA5 (0.45) | CYP2D6CYP3A4SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL29120613 | 0.78 | HPGD (0.48) | CYP2D6CYP3A4SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL10617353 | 0.77 | TSHR (0.55) | CYP2D6CYP3A4SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL11509581 | 0.76 | HSPA5 (0.48) | CYP2D6CYP3A4SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL29282177 | 0.75 | AKR1B1 (0.50) | CYP2D6SLC6A2SLC6A4SLC6A3HSPA5 | |
| SCHEMBL17123317 | 0.75 | HSPA5 (0.42) | CYP2D6CYP3A4SLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6727292-B2 | MIXING AND METERING TOGETHER AT LEAST THREE SEPARATE REACTIVE CHEMICAL COMPONENT STREAMS COMPRISING ISOCYANATE COMPOSITIONS AND POLYOLS | HUNTSMAN INTERNATIONAL LLC | 2004-04-27 | — | — | US | disclosed |
| US-20020040072-A1 | Manufacture of MDI-TDI based flexible polyurethane foams | HUNTSMAN INTERNATIONAL LLC | 2002-04-04 | — | — | US | disclosed |
| EP-0583929-B1 | Flexible polyurethane foams using chlorinated alkanes | ARCO CHEM TECH (US) | 1998-10-14 | — | — | EP | disclosed |
| EP-0406702-B1 | Preparation of polyurethane foams without using inert blowing agents | UNION CARBIDE CHEM PLASTIC (US) | 1997-03-05 | — | — | EP | disclosed |
| EP-0526178-B1 | Pour-in-place flexible polyurethane foam articles | ARCO CHEM TECH (US) | 1996-10-16 | — | — | EP | disclosed |
| US-5395860-A | Combustion resistance, durability | ARCO CHEMICAL TECHNOLOGY, L.P. (US) | 1995-03-07 | — | — | US | disclosed |
| EP-0583929-A1 | Flexible polyurethane foams using chlorinated alkanes | ARCO Chemical Technology, L.P. (US) | 1994-02-23 | — | — | EP | disclosed |
| EP-0526178-A2 | Pour-in-place flexible polyurethane foam articles | ARCO CHEMICAL TECHNOLOGY, INC. (US) | 1993-02-03 | — | — | EP | disclosed |
| EP-0492464-A2 | Reactive feed stream to replace inert blowing agent feed stream in a polyurethane foam process | UNION CARBIDE CHEMICALS AND PLASTICS COMPANY, INC. (US) | 1992-07-01 | — | — | EP | disclosed |
| US-5124368-A | Injecting reactants into mold bearing exterior covering without striking through, hydrophilic polyhydric compound with stabilizing effect | ARCO CHEMICAL TECHNOLOGY, L.P. (US) | 1992-06-23 | — | — | US | disclosed |
| US-4950694-A | Preparation of polyurethane foams without using inert blowing agents | UNION CARBIDE CHEMICALS AND PLASTICS COMPANY INC. (US) | 1990-08-21 | — | — | US | disclosed |
| US-4925890-A | SILICONE, ORGANOPHOSPHORUS PROCESSING AID | UNION CARBIDE CHEMICALS AND PLASTICS COMPANY INC. (US) | 1990-05-15 | — | — | US | disclosed |
| US-4857593-A | Process for processing thermoplastic polymers | UNION CARBIDE CORPORATION (US) | 1989-08-15 | — | — | US | disclosed |
| US-4849263-A | INJECTION MOLDING REINFORCEMENT GLASS FIBERS | UNION CARBIDE CORPORATION (US) | 1989-07-18 | — | — | US | disclosed |
| US-4804771-A | COUPLING AGENTS FOR GLASS FIBERS IN REINFORCED REACTION INJECTION MOLDING | UNION CARBIDE CORPORATION (US) | 1989-02-14 | — | — | US | disclosed |
| US-4622361-A | Flame retarded high modulus polyurethane elastomers and method of making same | UNION CARBIDE CORPORATION (US) | 1986-11-11 | — | — | US | disclosed |
| US-4563499-A | ADDITION-CONDENSATION GRAFT COPOLYMER | THE CELOTEX CORPORATION (US) | 1986-01-07 | — | — | US | disclosed |
| US-4546034-A | PANEL MADE OF PHENOLIC RESIN, POLYMER OF CYCLIC NITROGENOUS VIN MONOMER AND UNSATURATED ESTER | THE CELOTEX CORPORATION (US) | 1985-10-08 | — | — | US | disclosed |
| US-4522877-A | Extraction of polyoxyalkylene surfactants for phenolic foam stabilization | THE CELOTEX CORPORATION (US) | 1985-06-11 | — | — | US | disclosed |
| US-4520140-A | Polyoxyalkylene/unsaturated diester reaction product for cellular foam stabilization | THE CELOTEX CORPORATION (US) | 1985-05-28 | — | — | US | disclosed |