SCHEMBL231791

SCHEMBL231791

Oc1ccccc1CC(c1ccccc1O)c1ccccc1O

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSPA5 P11021 1/20 0.50
AKR1B1 P15121 1/20 0.48
TSHR P16473 2/20 0.47
GABRA1 P14867 1/20 0.46
GABRB2 P47870 1/20 0.46
CYP2D6 P10635 1/20 0.45
HIF1A Q16665 1/20 0.45
TAAR1 Q96RJ0 1/20 0.43
SLC6A2 P23975 1/20 0.42
SLC6A4 P31645 1/20 0.42
SLC6A3 Q01959 1/20 0.42
POLB P06746 2/20 0.42
MAPK1 P28482 1/20 0.42
IDO1 P14902 2/20 0.42
CA12 O43570 2/20 0.42
CA2 P00918 2/20 0.42
PKM P14618 1/20 0.41
HPGD P15428 1/20 0.41
CRHBP P24387 1/20 0.41
CRHR2 Q13324 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29611994 1.00 HSPA5 (0.50) HSPA5AKR1B1TSHRGABRA1GABRB2
SCHEMBL29120613 0.90 HPGD (0.48) HSPA5AKR1B1TSHRGABRA1GABRB2
SCHEMBL7799142 0.88 IAPP (0.46) HSPA5AKR1B1TSHRGABRA1GABRB2
SCHEMBL7809709 0.85 MPO (0.45) HSPA5AKR1B1TSHRGABRA1GABRB2
SCHEMBL18076591 0.84 TSHR (0.46) HSPA5AKR1B1TSHRGABRA1GABRB2
SCHEMBL6744900 0.83 CYP2D6 (0.51) HSPA5AKR1B1TSHRGABRA1GABRB2
SCHEMBL5440489 0.80 POLB (0.52) TSHRGABRA1GABRB2TAAR1SLC6A2
SCHEMBL983098 0.80 HSPA5 (0.52) HSPA5AKR1B1TSHRCYP2D6HIF1A
SCHEMBL30234428 0.80 HSPA5 (0.52) HSPA5AKR1B1TSHRCYP2D6HIF1A
SCHEMBL188373 0.79 TSHR (0.64) HSPA5AKR1B1TSHRGABRA1GABRB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 317 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4696729-A1 POLYURETHANE TOUGHENER SUITABLE FOR EPOXY COMPOSITION Henkel AG & Co. KGaA (DE) 2026-02-18 EP disclosed
EP-4631985-A1 A THERMALLY DEBONDABLE TWO-COMPONENT POLYURETHANE ADHESIVE COMPOSITION Henkel AG & Co. KGaA (DE) 2025-10-15 EP disclosed
EP-4600285-A1 FOAMABLE POLYURETHANE COMPOSITION COMPRISING A NITRILE Henkel AG & Co. KGaA (DE) 2025-08-13 EP disclosed
EP-4559947-A1 FOAMABLE POLYURETHANE COMPOSITION COMPRISING A FATTY AMIDE Henkel AG & Co. KGaA (DE) 2025-05-28 EP disclosed
EP-4553096-A1 POLYOL COMPONENT FOR THERMALLY CONDUCTIVE POLYURETHANE ADHESIVE COMPOSITION Henkel AG & Co. KGaA (DE) 2025-05-14 EP disclosed
EP-4549482-A1 THERMALLY CONDUCTIVE POLYURETHANE ADHESIVE COMPOSITION FOR BATTERIES IN ELECTRIC VEHICLES Henkel AG & Co. KGaA (DE) 2025-05-07 EP disclosed
US-20250129277-A1 TWO-PART POLYURETHANE-(METH) ACRYLIC HYBRID ADHESIVE COMPOSITION HENKEL AG & CO KGAA (DE) 2025-04-24 US disclosed
EP-3856813-B1 USE OF POLYVINYLACETATE POLYMERS OR COPOLYMERS TO INCREASE THE VISCOSITY OF THE ISOCYANATE COMPONENT OF A TWO-COMPONENT CURABLE POLYMERIC SYSTEM HENKEL AG & CO KGAA (DE) 2024-11-06 EP disclosed
US-12043731-B2 Use of polyvinylacetate polymers or copolymers to increase the viscosity of the isocyanate component of a two-component curable polymeric system HENKEL AG & CO. KGAA (DE) 2024-07-23 US disclosed
US-20240209247-A1 GREEN ALTERNATIVE POLYURETHANE ADHESIVE HENKEL AG & CO KGAA (DE) 2024-06-27 US disclosed
US-4258137-A INCORPORATING AN EPOXY RESIN AND CURING AGENT TO ATTAIN RIGIDITY W. R. GRACE & CO. (US) 1981-03-24 US disclosed
US-4250267-A Immobilized biological material W. R. GRACE & CO. (US) 1981-02-10 US disclosed
US-4237229-A CONTACTING A PROTEIN, ENZYME, COENZYME, OR ANTIBIOTIC WITH AN ISOCYANATE-CAPPED POLYETHERURETHANE COPOLYMER, SHAPING, AND CURING W. R. GRACE & CO. (US) 1980-12-02 US disclosed
US-4223099-A MULTISTAGE, ORGANIC DIOL, DIISOCYANATE BAYER AKTIENGESELLSCHAFT (DE) 1980-09-16 US disclosed
US-4195127-A Process for immobilizing proteins W. R. GRACE & CO. (US) 1980-03-25 US disclosed
EP-0003048-A1 Molding compositions consisting essentially of unsaturated polyesters, method of preparation and application BAYER AG (DE) 1979-07-25 EP disclosed
US-4107102-A POLY(ALKYLENE ETHER)POLYOL, HYDRAZINE DERIVATIVE, DIISOCYANATE, BLOWING AGENT BAYER AKTIENGESELLSCHAFT (DE) 1978-08-15 US disclosed
US-4098645-A Immobilization of proteins with polyurethane polymers W. R. GRACE & CO. (US) 1978-07-04 US disclosed
US-4094970-A ELASTOMERIC POLYURETHANE-BASED ARTICLES HAVING AN INSECTICIDAL DEPOT GAS ACTION BAYER AKTIENGESELLSCHAFT (DT) 1978-06-13 US disclosed
US-4094744-A IMMOBILIZED ENZYMES W. R. GRACE & CO. (US) 1978-06-13 US disclosed