SCHEMBL674494

SCHEMBL674494

C=CC1(OC(=O)/C=C\C(=O)O)CC1

nearest known ligand 0.40

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 8/20 0.40
TSHR P16473 2/20 0.36
TP53 P04637 1/20 0.36
EGLN1 Q9GZT9 1/20 0.36
EGLN3 Q9H6Z9 1/20 0.36
ATM Q13315 1/20 0.32
THRB P10828 1/20 0.31
CYP2C9 P11712 1/20 0.31
KDM4E B2RXH2 1/20 0.30
ALDH1A1 P00352 1/20 0.30
MAPT P10636 1/20 0.30
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2696997 1.00 HCAR2 (0.40) HCAR2TSHRTP53EGLN1EGLN3
SCHEMBL2360417 0.79 TSHR (0.32) TSHRTP53EGLN1EGLN3
Methacrylic Acid SCHEMBL726941 0.73 ALDH1A1 (0.31) ALDH1A1
SCHEMBL31564958 0.71 TSHR (0.31) TSHRTP53ALDH1A1
SCHEMBL8520653 0.69
SCHEMBL25509669 0.68
SCHEMBL24616746 0.68 HCAR2 (0.45) HCAR2TSHRTP53EGLN1EGLN3
SCHEMBL1402171 0.68 HCAR2 (0.45) HCAR2TSHRTP53EGLN1EGLN3
SCHEMBL1525228 0.68 HCAR2 (0.45) HCAR2TSHRTP53EGLN1EGLN3
SCHEMBL1402172 0.68 HCAR2 (0.45) HCAR2TSHRTP53EGLN1EGLN3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10569517-B2 Selectively permeable ethylene copolymer compositions PERFORMANCE MATERIALS NA, INC. (US) 2020-02-25 US disclosed
US-10435550-B2 Variable vapor barrier for humidity control PERFORMANCE MATERIALS NA, INC. (US) 2019-10-08 US disclosed
US-20180178496-A1 SELECTIVELY PERMEABLE ETHYLENE COPOLYMER COMPOSITIONS DOW GLOBAL TECHNOLOGIES LLC 2018-06-28 US disclosed
US-9777181-B2 Antistatic ethylene copolymer compositions E. I. DU PONT DE NEMOURS AND COMPANY (US) 2017-10-03 US disclosed
US-9777145-B2 Anti-fogging films based on ethylene copolymer compositions E. I. DU PONT DE NEMOURS AND COMPANY (US) 2017-10-03 US disclosed
US-20160303837-A1 SELECTIVELY PERMEABLE ETHYLENE COPOLYMER COMPOSITIONS PERFORMANCE MATERIALS NA, INC. 2016-10-20 US disclosed
US-20160280897-A1 METHOD TO FORM AN AQUEOUS DISPERSION OF AN IONMOER-ETHYLENE COPOLYMER BLEND E. I. DU PONT DE NEMOURS AND COMPANY 2016-09-29 US disclosed
US-20160280600-A1 POLYMER-MODIFIED FIBER-CEMENT COMPOSITION E. I. DU PONT DE NEMOURS AND COMPANY 2016-09-29 US disclosed
US-9441100-B2 Blends of ethylene copolymers with high-frequency weldability E. I. DU PONT DE NEMOURS AND COMPANY (US) 2016-09-13 US disclosed
US-20150179315-A1 ANTISTATIC ETHYLENE COPOLYMER COMPOSITIONS PERFORMANCE MATERIALS NA, INC. 2015-06-25 US disclosed
US-20150175788-A1 BLENDS OF ETHYLENE COPOLYMERS WITH HIGH-FREQUENCY WELDABILITY DOW GLOBAL TECHNOLOGIES LLC 2015-06-25 US disclosed
US-8062757-B2 Toughened thermoplastic polyamide compositions E.I. DU PONT DE NEMOURS AND COMPANY (US) 2011-11-22 US disclosed
US-8057910-B2 Toughened thermoplastic polyamide compositions E. I. DU PONT DE NEMOURS AND COMPANY (US) 2011-11-15 US disclosed
US-20110117363-A1 Toughened thermoplastic polyamide compositions E.I. DU PONT DE NEMOURS AND COMPANY (US) 2011-05-19 US disclosed
US-7935765-B2 Miscible blends of ethylene copolymers with improved temperature resistance E. I. DU PONT DE NEMOURS AND COMPANY (US) 2011-05-03 US disclosed
US-20110086564-A1 Toughened thermoplastic polyamide compositions E. I. DU PONT DE NEMOURS AND COMPANY (US) 2011-04-14 US disclosed
US-7879949-B2 Blends of ethylene copolymers with high-frequency weldability E.I. DU PONT DE NEMOURS AND COMPANY (US) 2011-02-01 US disclosed
US-20090227739-A1 Miscible Blends of Ethylene Copolymers With Improved Temperature Resistance E. I. DU PONT DE NEMOURS AND COMPANY (US) 2009-09-10 US disclosed
US-20060160952-A1 Blends of ethylene copolymers with high-frequency weldability PERFORMANCE MATERIALS NA, INC. 2006-07-20 US disclosed
US-20060148988-A1 Miscible blends of ethylene copolymers with improved temperature resistance PERFORMANCE MATERIALS NA, INC. 2006-07-06 US disclosed