Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 9/20 | 0.62 |
| ▸ | MME | P08473 | 7/20 | 0.62 |
| ▸ | ACE2 | Q9BYF1 | 7/20 | 0.62 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.60 |
| ▸ | CPA1 | P15085 | 6/20 | 0.57 |
| ▸ | CTSB | P07858 | 1/20 | 0.57 |
| ▸ | CTSS | P25774 | 1/20 | 0.57 |
| ▸ | CTSK | P43235 | 1/20 | 0.57 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.57 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.57 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.57 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.57 |
| ▸ | CA2 | P00918 | 2/20 | 0.56 |
| ▸ | CA1 | P00915 | 1/20 | 0.56 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.55 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5926142 | 1.00 | ACE (0.62) | ACEMMEACE2PTPN1L3MBTL1 | |
| SCHEMBL8165005 | 0.93 | PTPN1 (0.67) | ACEPTPN1L3MBTL1CA2CA1 | |
| SCHEMBL8165003 | 0.93 | PTPN1 (0.67) | ACEPTPN1L3MBTL1CA2CA1 | |
| SCHEMBL3989759 | 0.92 | ACE (0.56) | ACEMMEACE2PTPN1L3MBTL1 | |
| SCHEMBL15037300 | 0.91 | MME (0.53) | ACEMMEACE2PTPN1L3MBTL1 | |
| SCHEMBL15037188 | 0.91 | MME (0.53) | ACEMMEACE2PTPN1L3MBTL1 | |
| SCHEMBL22449043 | 0.91 | MME (0.53) | ACEMMEACE2PTPN1L3MBTL1 | |
| SCHEMBL22448948 | 0.91 | MME (0.53) | ACEMMEACE2PTPN1L3MBTL1 | |
| SCHEMBL22449308 | 0.90 | ITGA4 (0.58) | ACEMMEACE2PTPN1L3MBTL1 | |
| SCHEMBL15037322 | 0.90 | ITGA4 (0.58) | ACEMMEACE2PTPN1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040110832-A1 | management, treatment and/or control of diseases caused in intrinsic clotting pathway utilizing factor IX such as stroke, myocardial infarction, aneurysm surgery, and deep vein thrombosis associated with surgical procedures etc | TRANSTECH PHARMA, LLC | 2004-06-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040110832-A1 | management, treatment and/or control of diseases caused in intrinsic clotting pathway utilizing factor IX such as stroke, myocardial infarction, aneurysm surgery, and deep vein thrombosis associated with surgical procedures etc | TFPI, F9, TFPI2 | ACE 316/4885MME 1231/4885ACE2 925/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.