Sugi Predict

Sugi Predict / Compounds / SCHEMBL6744985

SCHEMBL6744985

SCHEMBL6744985

N[C@@H](Cc1ccccc1)C(=O)Cl

nearest known ligand 0.70

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
▸ SLC7A5 Q01650 2/20 0.70
▸ ALPI P09923 1/20 0.70
▸ PKM P14618 1/20 0.70
▸ PTGS1 P23219 1/20 0.70
▸ XIAP P98170 1/20 0.70
▸ SLC15A1 P46059 1/20 0.59
▸ LTA4H P09960 1/20 0.56
▸ SLC1A3 P43003 2/20 0.55
▸ SLC1A2 P43004 2/20 0.55
▸ SLC1A1 P43005 2/20 0.55
▸ HDAC8 Q9BY41 2/20 0.53
▸ EPHX1 P07099 2/20 0.52
▸ CYP1A2 P05177 1/20 0.52
▸ LAP3 P28838 3/20 0.50
▸ ANPEP P15144 1/20 0.50
▸ CTSC P53634 1/20 0.50
▸ DPP4 P27487 1/20 0.49
▸ SRR Q9GZT4 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7247735 1.00 SLC7A5 (0.70) SLC7A5ALPIPKMPTGS1XIAP
Hydrochloric Acid SCHEMBL21410547 0.98 SLC7A5 (0.68) SLC7A5ALPIPKMPTGS1XIAP
Hydrochloric Acid SCHEMBL21410546 0.98 SLC7A5 (0.68) SLC7A5ALPIPKMPTGS1XIAP
Phenylalanine SCHEMBL27787917 0.84 SLC7A5 (0.85) SLC7A5ALPIPKMPTGS1XIAP
Dl-Phenylalanine SCHEMBL3963405 0.84 SLC7A5 (0.85) SLC7A5ALPIPKMPTGS1XIAP
Phenylalanine SCHEMBL8998194 0.84 SLC7A5 (0.85) SLC7A5ALPIPKMPTGS1XIAP
Phenylalanine SCHEMBL430397 0.84 SLC7A5 (0.85) SLC7A5ALPIPKMPTGS1XIAP
Dl-Phenylalanine SCHEMBL27787918 0.84 SLC7A5 (0.85) SLC7A5ALPIPKMPTGS1XIAP
Dl-Phenylalanine SCHEMBL5063626 0.83 SLC7A5 (0.92) SLC7A5ALPIPKMPTGS1XIAP
Phenylalanine SCHEMBL5063628 0.83 SLC7A5 (0.92) SLC7A5ALPIPKMPTGS1XIAP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120054626-A Solid Lewis acid catalyst and preparation method and application thereof 四川大学 2025-05-30 — — CN claimed
CN-119264599-A Preparation method of cellulose melamine resin composite material 广东扬格新材料科技有限公司 2025-01-07 — — CN claimed
EP-0543343-A2 Process for the preparation of alpha-hydroxy-beta-aminocarboxylic acids LONZA AG (CH) 1993-05-26 — — EP claimed
JP-4273835-A — — None — — JP disclosed
CN-120054626-A Solid Lewis acid catalyst and preparation method and application thereof 四川大学 2025-05-30 — — CN disclosed
CN-119264599-A Preparation method of cellulose melamine resin composite material 广东扬格新材料科技有限公司 2025-01-07 — — CN disclosed
EP-3782636-B1 RAPADOCINS, INHIBITORS OF EQUILIBRATIVE NUCLEOSIDE TRANSPORTER 1 AND USES THEREOF UNIV JOHNS HOPKINS (US) 2024-05-15 — — EP disclosed
US-11827920-B2 Nanostructure, a biosensor including the nanostructure, and a screening method POSTECH Research and Business Development Foundation (KR) 2023-11-28 — — US disclosed
US-11708391-B2 Rapaglutins, novel inhibitors of GLUT and use thereof THE JOHNS HOPKINS UNIVERSITY (US) 2023-07-25 — — US disclosed
US-11555054-B2 Rapadocins, inhibitors of equilibrative nucleoside transporter 1 and uses thereof THE JOHNS HOPKINS UNIVERSITY (US) 2023-01-17 — — US disclosed
EP-3102193-B1 ANTIBACTERIAL AGENTS: N(ALPHA)-AROYL-N-ARYL-PHENYLALANINAMIDES UNIV RUTGERS (US) 2023-01-11 — — EP disclosed
EP-3102193-A1 ANTIBACTERIAL AGENTS: N(ALPHA)-AROYL-N-ARYL-PHENYLALANINAMIDES Rutgers, The State University of New Jersey (US) 2016-12-14 — — EP disclosed
US-20160347708-A1 ANTIBACTERIAL AGENTS: N(ALPHA)-AROYL-N-ARYL-PHENYLALANINAMIDES RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY 2016-12-01 — — US disclosed
US-20160215070-A1 MICRO CHIRAL REGULATION CELLULOSE CHROMATOGRAPHY STATIONARY PHASE, PREPARATION METHOD AND USE THEREOF THE FOURTH MILITARY MEDICAL UNIVERSITY (CN) 2016-07-28 — — US disclosed
WO-2015120320-A1 ANTIBACTERIAL AGENTS: N(ALPHA)-AROYL-N-ARYL-PHENYLALANINAMIDES RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) 2015-08-13 — — WO disclosed
US-20040110228-A1 Combinatorial organic synthesis of unique biologically active compounds MCALPINE SHELLI R (US) 2004-06-10 — — US disclosed
US-6562840-B1 Non-peptidic inhibitors of proteolytic enzymes such as urokinase 3-DIMENSIONAL PHARMACEUTICALS, INC. 2003-05-13 — — US disclosed
US-5252707-A Controlling metabolic procersses MITSUI TOATSU CHEMICALS INCORPORATED (JP) 1993-10-12 — — US disclosed
JP-H04273835-A PRODUCTION OF OPTICALLY ACTIVE ALCOHOL TOKYO KASEI KOGYO KK 1992-09-30 — — JP disclosed
EP-0445299-A1 INOSITOL DERIVATIVE AND PRODUCTION THEREOF MITSUI TOATSU CHEMICALS, Inc. (JP) 1991-09-11 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040110228-A1 Combinatorial organic synthesis of unique biologically active compounds PCNA, TOP1, TOP2A SLC7A5 2543/4885ALPI 1862/4885PKM 3169/4885
US-11708391-B2 Rapaglutins, novel inhibitors of GLUT and use thereof SLC2A1, SLC2A4, SLC2A2 SLC7A5 138/4885ALPI 2470/4885PKM 2760/4885
US-20160347708-A1 ANTIBACTERIAL AGENTS: N(ALPHA)-AROYL-N-ARYL-PHENYLALANINAMIDES TYR, NAT1, AANAT SLC7A5 834/4885ALPI 2170/4885PKM 2567/4885
US-11555054-B2 Rapadocins, inhibitors of equilibrative nucleoside transporter 1 and uses thereof SLC29A1, SLC29A2, SLC2A1 SLC7A5 161/4885ALPI 869/4885PKM 801/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.