Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4369319 | 0.88 | GAA (0.43) | GAAMAPTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL14027623 | 0.86 | GAA (0.47) | GAAMAPTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL4820254 | 0.85 | MAPT (0.48) | GAAMAPTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL4823017 | 0.85 | MAPT (0.46) | GAAMAPTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL14027639 | 0.84 | MAPT (0.46) | GAAMAPTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL4157310 | 0.83 | MAPT (0.41) | GAAMAPTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL4816428 | 0.82 | MAPT (0.46) | GAAMAPTSMN1; SMN2THRBTSHR | |
| SCHEMBL14027670 | 0.82 | MAPT (0.41) | GAAMAPTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL14027616 | 0.81 | ACHE (0.46) | GAAMAPTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL14027594 | 0.80 | AURKA (0.48) | MAPTSMN1; SMN2KMT2ATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6699873-B1 | EATING DISORDERS | MILLENNIUM PHARMACEUTICALS, INC. | 2004-03-02 | — | — | US | disclosed |