Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6225188 | 0.88 | THRB (0.35) | THRB | |
| SCHEMBL27028519 | 0.84 | THRB (0.55) | THRBALDH1A1TSHR | |
| SCHEMBL504018 | 0.84 | THRB (0.55) | THRBALDH1A1TSHR | |
| SCHEMBL8968 | 0.84 | — | — | |
| Water SCHEMBL3827178 | 0.78 | THRB (0.50) | THRBALDH1A1TSHR | |
| SCHEMBL3230777 | 0.78 | THRB (0.50) | THRBALDH1A1TSHR | |
| Hydrochloric Acid SCHEMBL7537660 | 0.78 | — | — | |
| SCHEMBL21494164 | 0.78 | THRB (0.50) | THRBALDH1A1TSHR | |
| SCHEMBL129302 | 0.78 | — | — | |
| Ammonia Solution, Strong SCHEMBL8694521 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040209897-A1 | Mitogen activated protein kinase-activated protein kinase-2 inhibiting compounds | PHARMACIA CORPORATION | 2004-10-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040209897-A1 | Mitogen activated protein kinase-activated protein kinase-2 inhibiting compounds | MAPKAPK2, MAP3K2, MKNK2 | THRB 2220/4885ALDH1A1 4638/4885TSHR 3883/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.