Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | GAA | P10253 | 3/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.54 |
| ▸ | GSK3B | P49841 | 5/20 | 0.44 |
| ▸ | GSK3A | P49840 | 4/20 | 0.44 |
| ▸ | CDK5 | Q00535 | 4/20 | 0.44 |
| ▸ | CDK2 | P24941 | 4/20 | 0.44 |
| ▸ | PLK4 | O00444 | 3/20 | 0.44 |
| ▸ | AURKA | O14965 | 3/20 | 0.44 |
| ▸ | CHEK2 | O96017 | 3/20 | 0.44 |
| ▸ | CSNK1D | P48730 | 3/20 | 0.44 |
| ▸ | AURKB | Q96GD4 | 3/20 | 0.44 |
| ▸ | LCK | P06239 | 2/20 | 0.44 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.44 |
| ▸ | STK3 | Q13188 | 2/20 | 0.44 |
| ▸ | BLK | P51451 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7476995 | 0.78 | SMN1; SMN2 (0.55) | SMN1; SMN2GAAMAPTCYP1A2KDM4E | |
| SCHEMBL7102226 | 0.78 | — | — | |
| SCHEMBL8613496 | 0.75 | SMN1; SMN2 (0.34) | SMN1; SMN2GAAMAPTCYP1A2KDM4E | |
| SCHEMBL8790147 | 0.73 | SMN1; SMN2 (0.64) | SMN1; SMN2GAAMAPTCYP1A2KDM4E | |
| SCHEMBL2575044 | 0.73 | MAPT (1.00) | SMN1; SMN2GAAMAPTCYP1A2KDM4E | |
| SCHEMBL5937366 | 0.73 | CYP1A2 (1.00) | SMN1; SMN2GAAMAPTCYP1A2GSK3B | |
| SCHEMBL4162589 | 0.73 | CYP1A2 (0.50) | SMN1; SMN2GAACYP1A2 | |
| SCHEMBL9833524 | 0.73 | DHODH (0.57) | SMN1; SMN2GAAMAPTCYP1A2KDM4E | |
| SCHEMBL23697571 | 0.71 | NPC1 (0.47) | SMN1; SMN2GAAMAPTCYP1A2KDM4E | |
| SCHEMBL624418 | 0.71 | GAA (0.59) | SMN1; SMN2GAAMAPTCYP1A2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040092737-A1 | Benzopiperidine derivatives | EISAI CO., LTD. | 2004-05-13 | — | — | US | disclosed |
| US-6518423-B1 | These compounds are useful as drugs efficacious in the prevention and treatment of these various inflammatory diseases and immunologic diseases, such as rheumatoid arthritis, atopic dermatitis, psoriasis, asthma, and | EISAI CO., LTD. (JP) | 2003-02-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040092737-A1 | Benzopiperidine derivatives | HLA-DRB1, HRH1, HRH2 | SMN1; SMN2 4491/4885GAA 2552/4885MAPT 1257/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.