Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.51 |
| ▸ | RAD52 | P43351 | 1/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 6/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | S100B | P04271 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.37 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.37 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5352494 | 0.99 | GAA (0.50) | GAARAD52KCNH2MAPTMAPK1 | |
| SCHEMBL6744572 | 0.96 | GAA (0.48) | GAARAD52KCNH2MAPTMAPK1 | |
| Hydrochloric Acid SCHEMBL5355166 | 0.95 | GAA (0.47) | GAARAD52KCNH2MAPTMAPK1 | |
| SCHEMBL5707909 | 0.90 | GAA (0.58) | GAARAD52KCNH2MAPTMAPK1 | |
| SCHEMBL5707924 | 0.90 | GAA (0.54) | GAARAD52KCNH2MAPTMAPK1 | |
| Hydrochloric Acid SCHEMBL5707964 | 0.89 | GAA (0.56) | GAARAD52KCNH2MAPTMAPK1 | |
| Hydrochloric Acid SCHEMBL5707952 | 0.89 | GAA (0.53) | GAARAD52KCNH2MAPTMAPK1 | |
| SCHEMBL6746551 | 0.83 | MAPT (0.46) | GAARAD52KCNH2MAPTMAPK1 | |
| Hydrochloric Acid SCHEMBL5345638 | 0.82 | MAPT (0.45) | GAARAD52KCNH2MAPTMAPK1 | |
| SCHEMBL6746520 | 0.81 | GAA (0.54) | GAARAD52MAPTMAPK1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1462091-A1 | Composition for dyeing of keratinic fibers comprising a cationic derivative of p-phenylenediamine substituted by a diazacyclohexane or a diazacyloheptane | L'OREAL (FR) | 2004-09-29 | — | — | EP | claimed |
| US-7186277-B2 | Composition for dyeing keratin fibres, comprising a cationic para-phenylenediamine derivative substituted with a diazacyclohexane or diazacycloheptane ring | L'OREAL SA (FR) | 2007-03-06 | — | — | US | disclosed |