Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3189746 | 1.00 | MEN1 (0.41) | MEN1KMT2AALOX15TSHRALDH1A1 | |
| SCHEMBL6746077 | 1.00 | MEN1 (0.41) | MEN1KMT2AALOX15TSHRALDH1A1 | |
| SCHEMBL3189002 | 0.88 | MEN1 (0.42) | MEN1KMT2AALOX15TSHRALDH1A1 | |
| SCHEMBL3189013 | 0.88 | MEN1 (0.42) | MEN1KMT2AALOX15TSHRALDH1A1 | |
| SCHEMBL3189028 | 0.88 | MEN1 (0.42) | MEN1KMT2AALOX15TSHRALDH1A1 | |
| SCHEMBL3263140 | 0.86 | ADAM17 (0.48) | MEN1KMT2AALOX15TSHRALDH1A1 | |
| SCHEMBL3263138 | 0.86 | ADAM17 (0.48) | MEN1KMT2AALOX15TSHRALDH1A1 | |
| SCHEMBL3263133 | 0.86 | ADAM17 (0.48) | MEN1KMT2AALOX15TSHRALDH1A1 | |
| SCHEMBL3197332 | 0.83 | POLB (0.49) | MEN1KMT2ATSHRALDH1A1LMNA | |
| SCHEMBL3199029 | 0.83 | MEN1 (0.39) | MEN1KMT2AALOX15TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040087548-A1 | Fused cyclic succinimide compounds and analogs thereof, modulators of nuclear hormone receptor function | BRISTOL-MYERS SQUIBB COMPANY | 2004-05-06 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040087548-A1 | Fused cyclic succinimide compounds and analogs thereof, modulators of nuclear hormone receptor function | NCOA1, ESRRA, NR5A1 | MEN1 1676/4885KMT2A 1756/4885ALOX15 2222/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.