Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NISCH | Q9Y2I1 | 11/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.34 |
| ▸ | MC4R | P32245 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6745405 | 0.77 | NISCH (0.51) | NISCHGAATSHR | |
| SCHEMBL6745419 | 0.76 | NISCH (0.48) | NISCHGAATSHR | |
| SCHEMBL4063712 | 0.72 | NISCH (0.50) | NISCHGAATSHR | |
| Bromide SCHEMBL4912493 | 0.71 | NISCH (0.49) | NISCHGAATSHR | |
| SCHEMBL7561038 | 0.70 | NISCH (0.54) | NISCH | |
| SCHEMBL4822597 | 0.68 | NISCH (0.80) | NISCHGAATSHR | |
| SCHEMBL8517160 | 0.66 | LIPG (0.49) | KCNH2 | |
| SCHEMBL8517066 | 0.66 | LIPG (0.49) | KCNH2 | |
| SCHEMBL8518028 | 0.66 | LIPG (0.49) | KCNH2 | |
| SCHEMBL8517192 | 0.66 | LIPG (0.49) | KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6699873-B1 | EATING DISORDERS | MILLENNIUM PHARMACEUTICALS, INC. | 2004-03-02 | — | — | US | disclosed |