SCHEMBL6746282

SCHEMBL6746282

NC(=O)c1ccccc1SO

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SIRT1 Q96EB6 1/20 0.62
KDM4E B2RXH2 4/20 0.52
ALDH1A1 P00352 4/20 0.52
MAPT P10636 3/20 0.52
TSHR P16473 2/20 0.52
HSD17B10 Q99714 2/20 0.52
HPGD P15428 2/20 0.52
METAP2 P50579 1/20 0.48
BCAT2 O15382 1/20 0.47
POLB P06746 2/20 0.45
GAA P10253 1/20 0.42
CTNNB1 P35222 1/20 0.42
NPC1 O15118 2/20 0.41
IRAK4 Q9NWZ3 1/20 0.41
RAB9A P51151 1/20 0.41
KEAP1 Q14145 1/20 0.41
NFE2L2 Q16236 1/20 0.41
PARP1 P09874 2/20 0.41
CYP3A4 P08684 1/20 0.41
CYP2C19 P33261 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1399456 0.84 SIRT1 (0.64) SIRT1KDM4EALDH1A1MAPTTSHR
SCHEMBL11821622 0.84 SIRT1 (0.64) SIRT1KDM4EALDH1A1MAPTTSHR
SCHEMBL3077375 0.84 SIRT1 (0.77) SIRT1KDM4EALDH1A1MAPTTSHR
SCHEMBL29530768 0.84 SIRT1 (0.64) SIRT1KDM4EALDH1A1MAPTTSHR
SCHEMBL29084170 0.80 SIRT1 (0.60) SIRT1KDM4EALDH1A1MAPTTSHR
SCHEMBL701691 0.80 SIRT1 (0.60) SIRT1KDM4EALDH1A1MAPTTSHR
SCHEMBL7418361 0.80 SIRT1 (0.60) SIRT1KDM4EALDH1A1MAPTTSHR
SCHEMBL16534310 0.79 POLB (0.71) KDM4EALDH1A1MAPTHPGDPOLB
Iodide SCHEMBL7710889 0.78 SIRT1 (0.58) SIRT1KDM4EALDH1A1MAPTTSHR
SCHEMBL3066455 0.77 CA12 (0.48) SIRT1KDM4EALDH1A1MAPTHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0241735-A2 Acyloxythiophene carbon amide BAYER AG (DE) 1987-10-21 EP claimed
CN-1260010-C Ethene oligomerization catalyst, synthetic method and use thereof SHANGHAI ORGANIC CHEMICAL INST (CN) 2006-06-21 CN disclosed
CN-1218970-C New olefine polymerization catalyst SHANGHAI INST ORGANIC CHEM (CN) 2005-09-14 CN disclosed
CN-1552525-A Ethene oligomerization catalyst, synthetic method and use thereof 中国科学院上海有机化学研究所 2004-12-08 CN disclosed
US-6696380-B2 Procatalysts, catalyst systems, and use in olefin polymerization WESTLAKE LONGVIEW CORPORATION 2004-02-24 US disclosed
US-6677410-B2 COORDINATION CATALYSTS EASTMAN CHEMICAL COMPANY 2004-01-13 US disclosed
US-6677266-B1 CONTACTING MAGNESIUM CHLORIDE WITH A VANADIUM COMPOUND CONTAINING AT LEAST ONE ELECTRON DONOR THEREBY YIELDING A PRODUCT THAT IS THEREAFTER CONTACTED WITH A TITANIUM COMPOUND EASTMAN CHEMICAL COMPANY 2004-01-13 US disclosed
US-20030004285-A1 Procatalysts, catalyst systems, and use in olefin polymerization WESTLAKE LONGVIEW CORPORATION 2003-01-02 US disclosed
US-6465383-B2 COORDINATION CATALYST EASTMAN CHEMICAL COMPANY 2002-10-15 US disclosed
CN-1364818-A New olefine polymerization catalyst SHANGHAI INST ORGANIC CHEM (CN) 2002-08-21 CN disclosed
US-20010051587-A1 Procatalysts, catalyst systems, and use in olefin polymerization WESTLAKE LONGVIEW CORPORATION 2001-12-13 US disclosed
US-20010031841-A1 Procatalysts, catalyst systems, and use in olefin polymerization WESTLAKE LONGVIEW CORPORATION 2001-10-18 US disclosed
US-20010025005-A1 Procatalysts, catalyst systems, and use in olefin polymerization EASTMAN CHEMICAL COMPANY, A CORPORATION OF DELAWARE 2001-09-27 US disclosed
WO-2001051526-A1 PROCATALYSTS COMPRISING BIDENTATE LIGANDS, CATALYST SYSTEMS, AND USE IN OLEFIN POLYMERIZATION EASTMAN CHEMICAL COMPANY (US) 2001-07-19 WO disclosed
WO-2001051529-A1 PROCATALYSTS COMPRISING BIDENTATE LIGANDS, CATALYST SYSTEMS, AND USE IN OLEFIN POLYMERIZATION EASTMAN CHEMICAL COMPANY (US) 2001-07-19 WO disclosed
WO-2001051528-A1 PROCATALYSTS COMPRISING BIDENTATE LIGANDS, CATALYST SYSTEMS, AND USE IN OLEFIN POLYMERIZATION EASTMAN CHEMICAL COMPANY (US) 2001-07-19 WO disclosed
EP-0289171-A1 Substituted 2H-benzoxazin-2-ones UNIROYAL CHEMICAL COMPANY, Inc. (US) 1988-11-02 EP disclosed
EP-0241735-A2 Acyloxythiophene carbon amide BAYER AG (DE) 1987-10-21 EP disclosed