Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.35 |
| ▸ | GABBR2 | O75899 | 2/20 | 0.33 |
| ▸ | GABBR1 | Q9UBS5 | 2/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.32 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.31 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL725910 | 0.94 | — | — | |
| SCHEMBL20365804 | 0.77 | ALDH1A1 (0.38) | ALDH1A1DPP4TRPV1TRPA1 | |
| SCHEMBL27335038 | 0.77 | ALDH1A1 (0.35) | ALDH1A1GABRR1GABBR2GABBR1TRPV1 | |
| SCHEMBL21973386 | 0.77 | — | — | |
| SCHEMBL727485 | 0.77 | — | — | |
| SCHEMBL648050 | 0.75 | — | — | |
| Hydrochloric Acid SCHEMBL5463908 | 0.74 | TRPV1 (0.35) | ALDH1A1DPP4TRPV1TRPA1 | |
| SCHEMBL13532953 | 0.74 | GSR (0.41) | TRPV1TRPA1 | |
| SCHEMBL4795508 | 0.74 | GSR (0.41) | TRPV1TRPA1 | |
| SCHEMBL9420958 | 0.74 | ALDH1A1 (0.53) | ALDH1A1GABRR1GABBR2GABBR1TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6689919-B1 | SOLUBLE POLY(OXYFLUOROPHENYLENE) COMPOUNDS WITH EXCELLENT HEAT RESISTANCE, MEMBRANE-FORMABILITY AND CHEMICAL STABILITY | JAPAN SCIENCE AND TECHNOLOGY CORPORATION (JP) | 2004-02-10 | — | — | US | disclosed |