Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.55 |
| ▸ | RAD52 | P43351 | 1/20 | 0.55 |
| ▸ | CHRNA10 | Q9GZZ6 | 10/20 | 0.45 |
| ▸ | CHRNA9 | Q9UGM1 | 10/20 | 0.45 |
| ▸ | CHRNA7 | P36544 | 8/20 | 0.45 |
| ▸ | LGMN | Q99538 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | S100B | P04271 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5345795 | 0.99 | GAA (0.53) | GAARAD52CHRNA10CHRNA9CHRNA7 | |
| SCHEMBL6746050 | 0.95 | GAA (0.50) | GAARAD52CHRNA10CHRNA9CHRNA7 | |
| Hydrochloric Acid SCHEMBL5362799 | 0.94 | GAA (0.49) | GAARAD52CHRNA10CHRNA9CHRNA7 | |
| SCHEMBL14559154 | 0.93 | GAA (0.55) | GAARAD52CHRNA10CHRNA9CHRNA7 | |
| Hydrochloric Acid SCHEMBL5346509 | 0.92 | GAA (0.54) | GAARAD52CHRNA10CHRNA9CHRNA7 | |
| SCHEMBL6748617 | 0.88 | GAA (0.50) | GAARAD52CHRNA10CHRNA9CHRNA7 | |
| Hydrochloric Acid SCHEMBL5397681 | 0.87 | GAA (0.49) | GAARAD52CHRNA10CHRNA9CHRNA7 | |
| SCHEMBL6746520 | 0.84 | GAA (0.54) | GAARAD52CHRNA10CHRNA9CHRNA7 | |
| Hydrochloric Acid SCHEMBL5349256 | 0.83 | GAA (0.52) | GAARAD52CHRNA10CHRNA9CHRNA7 | |
| SCHEMBL6745286 | 0.82 | CHRNA10 (0.54) | GAARAD52CHRNA10CHRNA9CHRNA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1462091-A1 | Composition for dyeing of keratinic fibers comprising a cationic derivative of p-phenylenediamine substituted by a diazacyclohexane or a diazacyloheptane | L'OREAL (FR) | 2004-09-29 | — | — | EP | claimed |
| US-7186277-B2 | Composition for dyeing keratin fibres, comprising a cationic para-phenylenediamine derivative substituted with a diazacyclohexane or diazacycloheptane ring | L'OREAL SA (FR) | 2007-03-06 | — | — | US | disclosed |