Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 5/20 | 0.42 |
| ▸ | CNR1 | P21554 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.36 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 2/20 | 0.35 |
| ▸ | PDE5A | O76074 | 1/20 | 0.35 |
| ▸ | PDE4A | P27815 | 1/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1522543 | 0.89 | MAPK1 (0.45) | CNR2CNR1MAPK1HSD17B10MEN1 | |
| SCHEMBL1523712 | 0.89 | CNR2 (0.45) | CNR2CNR1MAPK1HSD17B10MEN1 | |
| SCHEMBL27649401 | 0.88 | CNR2 (0.45) | CNR2CNR1MAPK1HSD17B10MEN1 | |
| SCHEMBL1522681 | 0.88 | CNR2 (0.41) | CNR2CNR1MAPK1HSD17B10MEN1 | |
| SCHEMBL1522434 | 0.87 | MAPK1 (0.45) | CNR2CNR1MAPK1HSD17B10MEN1 | |
| SCHEMBL1523047 | 0.86 | MAPK1 (0.47) | CNR2CNR1MAPK1HSD17B10MEN1 | |
| SCHEMBL1522772 | 0.86 | CNR2 (0.45) | CNR2CNR1MAPK1HSD17B10MEN1 | |
| SCHEMBL1522605 | 0.85 | MAPK1 (0.47) | CNR2CNR1MAPK1HSD17B10MEN1 | |
| SCHEMBL1523362 | 0.85 | MAPK1 (0.43) | CNR2CNR1MAPK1HSD17B10MEN1 | |
| SCHEMBL1522984 | 0.85 | CNR2 (0.41) | CNR2CNR1MAPK1HSD17B10MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040162285-A1 | Anti-infective agents | ABBOTT LABORATORIES | 2004-08-19 | — | — | US | claimed |
| US-20040097492-A1 | Anti-infective agents | ABBOTT LABORATORIES | 2004-05-20 | — | — | US | claimed |
| US-20040087577-A1 | Anti-infective agents | ABBOTT LABORATORIES | 2004-05-06 | — | — | US | claimed |
| US-20040162285-A1 | Anti-infective agents | ABBOTT LABORATORIES | 2004-08-19 | — | — | US | disclosed |
| US-20040097492-A1 | Anti-infective agents | ABBOTT LABORATORIES | 2004-05-20 | — | — | US | disclosed |
| US-20040087577-A1 | Anti-infective agents | ABBOTT LABORATORIES | 2004-05-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040097492-A1 | Anti-infective agents | POLR1C, RPL5, POLB | CNR2 4494/4885CNR1 3398/4885MAPK1 1456/4885 |
| US-20040162285-A1 | Anti-infective agents | POLR1C, RPL5, POLB | CNR2 4494/4885CNR1 3398/4885MAPK1 1456/4885 |
| US-20040087577-A1 | Anti-infective agents | POLR1C, RPL5, POLB | CNR2 4494/4885CNR1 3398/4885MAPK1 1456/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.