Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.40 |
| ▸ | ICAM1 | P05362 | 4/20 | 0.31 |
| ▸ | CLK1 | P49759 | 4/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.30 |
| ▸ | PIM1 | P11309 | 2/20 | 0.30 |
| ▸ | CSNK1D | P48730 | 2/20 | 0.30 |
| ▸ | CSNK1E | P49674 | 2/20 | 0.30 |
| ▸ | CLK3 | P49761 | 2/20 | 0.30 |
| ▸ | CSNK1G2 | P78368 | 2/20 | 0.30 |
| ▸ | MAP3K19 | Q56UN5 | 2/20 | 0.30 |
| ▸ | PIM3 | Q86V86 | 2/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.30 |
| ▸ | DYRK1B | Q9Y463 | 2/20 | 0.30 |
| ▸ | CSNK1G3 | Q9Y6M4 | 2/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6749072 | 0.90 | HDAC6 (0.38) | HDAC6 | |
| SCHEMBL6751926 | 0.88 | HDAC6 (0.38) | HDAC6 | |
| SCHEMBL6749341 | 0.87 | HDAC6 (0.39) | HDAC6THRB | |
| SCHEMBL6749473 | 0.86 | HDAC6 (0.35) | HDAC6 | |
| SCHEMBL6749761 | 0.86 | HDAC6 (0.40) | HDAC6ICAM1CLK1THRBDYRK1A | |
| SCHEMBL6749766 | 0.86 | HDAC6 (0.40) | HDAC6ICAM1CLK1THRBDYRK1A | |
| SCHEMBL6745548 | 0.86 | HDAC6 (0.36) | HDAC6CLK1THRBDYRK1APIM1 | |
| SCHEMBL6747294 | 0.86 | HDAC6 (0.39) | HDAC6ICAM1 | |
| SCHEMBL6749064 | 0.86 | HDAC6 (0.41) | HDAC6ICAM1THRB | |
| SCHEMBL6746539 | 0.86 | HDAC6 (0.41) | HDAC6ICAM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040092737-A1 | Benzopiperidine derivatives | EISAI CO., LTD. | 2004-05-13 | — | — | US | disclosed |
| US-6518423-B1 | These compounds are useful as drugs efficacious in the prevention and treatment of these various inflammatory diseases and immunologic diseases, such as rheumatoid arthritis, atopic dermatitis, psoriasis, asthma, and | EISAI CO., LTD. (JP) | 2003-02-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040092737-A1 | Benzopiperidine derivatives | HLA-DRB1, HRH1, HRH2 | HDAC6 1953/4885ICAM1 412/4885CLK1 4545/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.