SCHEMBL6747598

SCHEMBL6747598

C=C(C)C(=O)OC[Si](CCC)(CCC)CCC

nearest known ligand 0.48

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.48
THRB P10828 1/20 0.46
ALDH1A1 P00352 5/20 0.39
POLB P06746 1/20 0.31
APEX1 P27695 1/20 0.31
HTT P42858 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
LMNA P02545 1/20 0.30
HSD17B10 Q99714 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25289108 0.82 TSHR (0.47) TSHRTHRBALDH1A1POLBAPEX1
SCHEMBL23908685 0.81 TSHR (0.46) TSHRTHRBALDH1A1
SCHEMBL16537473 0.79 TSHR (0.44) TSHRTHRBALDH1A1
SCHEMBL16537776 0.79 TSHR (0.44) TSHRTHRBALDH1A1
SCHEMBL1322124 0.79 TSHR (0.62) TSHRTHRBALDH1A1POLBAPEX1
SCHEMBL16536853 0.78 THRB (0.44) TSHRTHRBALDH1A1LMNAHSD17B10
SCHEMBL1403516 0.78 TSHR (0.47) TSHRTHRBALDH1A1
SCHEMBL12272566 0.78 TSHR (0.43) TSHRTHRBALDH1A1
SCHEMBL16537246 0.78 THRB (0.44) TSHRTHRBALDH1A1LMNAHSD17B10
SCHEMBL29913923 0.78 TSHR (0.45) TSHRTHRBALDH1A1POLBAPEX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20030125467-A1 A crosslinked rubber particles containing conjugated diene monomer, aromatic vinyl monomer and monomer with at least two polymerizable unsaturated groups dispersed in a conjugated diene/aromatic vinyl copolymer; resist to rolling, skid, wear JSR CORPORATION (JP) 2003-07-03 US claimed
CN-110408206-A Polyamic acid resin composition, preparation method and the film formed by the composition WUXI CHUANGCAI OPTICAL MAT CO LTD 2019-11-05 CN disclosed
US-6699935-B2 A CROSSLINKED RUBBER PARTICLES CONTAINING CONJUGATED DIENE MONOMER, AROMATIC VINYL MONOMER AND MONOMER WITH AT LEAST TWO POLYMERIZABLE UNSATURATED GROUPS DISPERSED IN A CONJUGATED DIENE/AROMATIC VINYL COPOLYMER; RESIST TO ROLLING, SKID, WEAR JSR CORPORATION (JP) 2004-03-02 US disclosed
US-20030125467-A1 A crosslinked rubber particles containing conjugated diene monomer, aromatic vinyl monomer and monomer with at least two polymerizable unsaturated groups dispersed in a conjugated diene/aromatic vinyl copolymer; resist to rolling, skid, wear JSR CORPORATION (JP) 2003-07-03 US disclosed