SCHEMBL674764

SCHEMBL674764

COc1ccc(C#Cc2ccc(OC)cc2)cc1

nearest known ligand 0.77

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
APP P05067 3/20 0.77
CA1 P00915 2/20 0.65
CA2 P00918 2/20 0.65
CA7 P43166 2/20 0.65
CA9 Q16790 2/20 0.65
CA12 O43570 1/20 0.65
CA14 Q9ULX7 1/20 0.65
KCNH2 Q12809 1/20 0.63
ACHE P22303 1/20 0.52
ACACB O00763 2/20 0.52
MCHR1 Q99705 1/20 0.52
TDP1 Q9NUW8 3/20 0.50
MAPK1 P28482 2/20 0.50
KDM4E B2RXH2 1/20 0.48
NPC1 O15118 1/20 0.48
GAA P10253 1/20 0.48
MAPT P10636 1/20 0.48
THRB P10828 1/20 0.48
RECQL P46063 1/20 0.48
RAB9A P51151 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10300057 1.00 APP (0.77) APPCA1CA2CA7CA9
SCHEMBL9715639 0.97 APP (0.74) APPCA1CA2CA7CA9
SCHEMBL21903457 0.92 APP (0.75) APPCA1CA2CA7CA9
SCHEMBL9333443 0.90 APP (0.72) APPCA1CA2CA7CA9
SCHEMBL5552160 0.90 APP (0.65) APPCA1CA2CA7CA9
SCHEMBL10525794 0.90 ACHE (0.71) APPCA1CA2CA7CA9
SCHEMBL7134534 0.89 APP (0.64) APPCA1CA2CA7CA9
SCHEMBL13863705 0.88 APP (0.63) APPCA1CA2CA7CA9
SCHEMBL709673 0.88 APP (0.63) APPCA1CA2CA7CA9
SCHEMBL4457311 0.88 APP (0.63) APPCA1CA2CA7CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 155 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119661581-A Fused ring tin porphyrin photosensitizer with high singlet oxygen sensitization efficiency and photothermal effect 四川大学华西医院 2025-03-21 CN claimed
CN-119505583-A Preparation method of high-temperature-resistant bending-resistant insulating paint 深圳清研皓隆新能源科技有限公司 2025-02-25 CN claimed
CN-119371309-A Indenoacetates method for synthesizing compound 南通大学 2025-01-28 CN claimed
CN-117285454-A Synthesis method of indole derivative and benzodipyrrole derivative 南京邮电大学 2023-12-26 CN claimed
CN-116653382-A High-low temperature resistant toughened palm fiber triangular belt and preparation method thereof 河南双力橡胶股份有限公司 2023-08-29 CN claimed
CN-116536011-A High-specific gravity epoxy balance daub and preparation method thereof 嘉兴市韶华塑胶新材料股份有限公司 2023-08-04 CN claimed
CN-113200913-B Light-activated type I photosensitizer and preparation method and application thereof 华南理工大学 2022-10-21 CN claimed
CN-110028394-B Synthetic method of indanone and derivatives thereof 南京邮电大学 2021-09-17 CN claimed
CN-104892377-B A kind of synthetic method of 1,2 derovatives 上海交通大学 2018-01-19 CN claimed
CN-106883188-A A kind of benzodiazepine compounds of 5 hydrogen 1,4 and its synthetic method 上海交通大学 2017-06-23 CN claimed
CN-120059050-A Preparation method and application of amphiphilic phosphine-containing porous organic copolymer supported palladium metal catalyst 青岛科技大学 2025-05-30 CN disclosed
US-12292665-B2 Bistable liquid crystal dispersion devices comprising metal-organic mesogens and applications thereof GAUZY LTD. (IL) 2025-05-06 US disclosed
CN-119661581-A Fused ring tin porphyrin photosensitizer with high singlet oxygen sensitization efficiency and photothermal effect 四川大学华西医院 2025-03-21 CN disclosed
CN-119505583-A Preparation method of high-temperature-resistant bending-resistant insulating paint 深圳清研皓隆新能源科技有限公司 2025-02-25 CN disclosed
CN-119371309-A Indenoacetates method for synthesizing compound 南通大学 2025-01-28 CN disclosed
US-4101207-A Preparation of liquid crystal containing polymeric structure OWENS-ILLINOIS, INC. (US) 1978-07-18 US disclosed
US-4012434-A Nematic compounds and mixtures MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DT) 1977-03-15 US disclosed
US-4002670-A 4'-ALKOXY OR ALKYL PHENYL ESTERS OF 4-ALKYL OR ALKOXY BENZOIC ACIDS MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DT) 1977-01-11 US disclosed
US-4001137-A Nematic compounds and mixtures MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DT) 1977-01-04 US disclosed
US-3935337-A Preparation of liquid crystal containing polymeric structure OWENS-ILLINOIS, INC. (US) 1976-01-27 US disclosed