Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4436457 | 0.87 | HMGCR (0.31) | — | |
| SCHEMBL4063762 | 0.87 | HMGCR (0.31) | — | |
| SCHEMBL1991587 | 0.83 | HMGCR (0.31) | — | |
| SCHEMBL10015623 | 0.77 | BUB1 (0.31) | — | |
| SCHEMBL10024055 | 0.72 | HMGCR (0.37) | — | |
| SCHEMBL10024065 | 0.72 | HMGCR (0.32) | — | |
| SCHEMBL433791 | 0.72 | HMGCR (0.32) | — | |
| SCHEMBL6747790 | 0.72 | SMN1; SMN2 (0.39) | THRBALOX15 | |
| SCHEMBL9269812 | 0.71 | HMGCR (0.38) | — | |
| SCHEMBL4643619 | 0.71 | HMGCR (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8471045-B2 | Synthesis of statins | LEK PHARMACEUTICALS D.D. (SI) | 2013-06-25 | — | — | US | disclosed |
| US-20120196333-A1 | SYNTHESIS OF STATINS | LEK PHARMACEUTICALS D.D. (SI) | 2012-08-02 | — | — | US | disclosed |
| US-8183397-B2 | Synthesis of statins | LEK PHARMACEUTICALS D.D. (SI) | 2012-05-22 | — | — | US | disclosed |
| US-20110178295-A1 | SYNTHESIS OF STATINS | LEK PHARMACEUTICALS D.D. (SI) | 2011-07-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110178295-A1 | SYNTHESIS OF STATINS | HMGCR, DHCR7, COASY | THRB 3024/4885ALOX15 627/4885 |
| US-20120196333-A1 | SYNTHESIS OF STATINS | HMGCR, DHCR7, COASY | THRB 3024/4885ALOX15 627/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.