Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGCR | P04035 | 5/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 5/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.38 |
| ▸ | PRKCA | P17252 | 1/20 | 0.31 |
| ▸ | PPM1D | O15297 | 2/20 | 0.31 |
| ▸ | TOP2A | P11388 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10024054 | 1.00 | HMGCR (0.38) | HMGCRHDAC1HDAC2HDAC6PRKCA | |
| SCHEMBL2067039 | 1.00 | HMGCR (0.38) | HMGCRHDAC1HDAC2HDAC6PRKCA | |
| SCHEMBL9269812 | 1.00 | HMGCR (0.38) | HMGCRHDAC1HDAC2HDAC6PRKCA | |
| SCHEMBL10024025 | 1.00 | HMGCR (0.38) | HMGCRHDAC1HDAC2HDAC6PRKCA | |
| SCHEMBL4440967 | 1.00 | HMGCR (0.38) | HMGCRHDAC1HDAC2HDAC6PRKCA | |
| SCHEMBL22722148 | 0.89 | HMGCR (0.41) | HMGCRHDAC1HDAC2HDAC6PRKCA | |
| SCHEMBL10024055 | 0.87 | HMGCR (0.37) | HMGCRHDAC1HDAC2HDAC6PPM1D | |
| SCHEMBL2168815 | 0.85 | HMGCR (0.36) | HMGCRHDAC1HDAC2HDAC6PPM1D | |
| SCHEMBL2167968 | 0.85 | HMGCR (0.36) | HMGCRHDAC1HDAC2HDAC6TOP2A | |
| SCHEMBL4595118 | 0.85 | HMGCR (0.36) | HMGCRHDAC1HDAC2HDAC6TOP2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1234884-B1 | A process for the preparation of beta-hydroxy-delta-lactone using novel intermediates | COUNCIL SCIENT IND RES (IN) | 2008-08-20 | — | — | EP | claimed |
| EP-1234884-A1 | A process for the preparation of beta-hydroxy-delta-lactone using novel intermediates | Council of Scientific & Industrial Research (IN) | 2002-08-28 | — | — | EP | claimed |
| US-6388097-B1 | USING 3-HYDROXY-5-(TERT-BUTYLDIMETHYLSILYLOXY) CYCLOHEXYLACETATE | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2002-05-14 | — | — | US | claimed |
| EP-1234884-B1 | A process for the preparation of beta-hydroxy-delta-lactone using novel intermediates | COUNCIL SCIENT IND RES (IN) | 2008-08-20 | — | — | EP | disclosed |
| EP-1234884-A1 | A process for the preparation of beta-hydroxy-delta-lactone using novel intermediates | Council of Scientific & Industrial Research (IN) | 2002-08-28 | — | — | EP | disclosed |
| EP-1234884-A1 | A process for the preparation of beta-hydroxy-delta-lactone using novel intermediates | Council of Scientific & Industrial Research (IN) | 2002-08-28 | — | — | EP | disclosed |
| US-6388097-B1 | USING 3-HYDROXY-5-(TERT-BUTYLDIMETHYLSILYLOXY) CYCLOHEXYLACETATE | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2002-05-14 | — | — | US | disclosed |