Sugi Predict

Sugi Predict / Compounds / 2-Picolinic Acid

2-Picolinic Acid

2-Picolinic Acid

SCHEMBL674850

O=C([O-])c1ccccn1.O=C([O-])c1ccccn1.[Fe+2]

nearest known ligand 0.64

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CES2 O00748 1/20 0.64
▸ CES1 P23141 1/20 0.64
▸ L3MBTL1 Q9Y468 3/20 0.61
▸ LMNA P02545 3/20 0.61
▸ P4HTM Q9NXG6 2/20 0.61
▸ NAPRT Q6XQN6 1/20 0.61
▸ ALDH1A1 P00352 2/20 0.59
▸ KMT2A Q03164 1/20 0.55
▸ GSK3B P49841 1/20 0.53
▸ KDM4E B2RXH2 4/20 0.47
▸ NPC1 O15118 2/20 0.47
▸ RAB9A P51151 2/20 0.47
▸ MAPT P10636 1/20 0.47
▸ PKM P14618 1/20 0.47
▸ HDAC3 O15379 1/20 0.46
▸ HDAC4 P56524 1/20 0.46
▸ HDAC1 Q13547 1/20 0.46
▸ HDAC7 Q8WUI4 1/20 0.46
▸ HDAC2 Q92769 1/20 0.46
▸ HDAC10 Q969S8 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
2-Picolinic Acid SCHEMBL11378795 0.98 CES2 (0.67) CES2CES1L3MBTL1LMNAP4HTM
2-Picolinic Acid SCHEMBL1462619 0.95 CES2 (0.64) CES2CES1L3MBTL1LMNAP4HTM
2-Picolinic Acid SCHEMBL15401421 0.95 CES2 (0.64) CES2CES1L3MBTL1LMNAP4HTM
2-Picolinic Acid SCHEMBL15271681 0.95 CES2 (0.64) CES2CES1L3MBTL1LMNAP4HTM
2-Picolinic Acid SCHEMBL11378797 0.95 CES2 (0.64) CES2CES1L3MBTL1LMNAP4HTM
2-Picolinic Acid SCHEMBL5058098 0.95 CES2 (0.64) CES2CES1L3MBTL1LMNAP4HTM
2-Picolinic Acid SCHEMBL5354659 0.95 CES2 (0.64) CES2CES1L3MBTL1LMNAP4HTM
2-Picolinic Acid SCHEMBL432467 0.95 CES2 (0.64) CES2CES1L3MBTL1LMNAP4HTM
2-Picolinic Acid SCHEMBL524041 0.95 CES2 (0.64) CES2CES1L3MBTL1LMNAP4HTM
2-Picolinic Acid SCHEMBL673572 0.95 CES2 (0.64) CES2CES1L3MBTL1LMNAP4HTM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 176 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12268676-B2 Antiviral applications of picolinic acid and its derivatives INDIAN INSTITUTE OF SCIENCE (IN) 2025-04-08 — — US claimed
CN-114685702-B Method for preparing poly-conjugated diene by using pyridine imine iron catalyst and application of poly-conjugated diene 中国科学院青岛生物能源与过程研究所 2023-08-18 — — CN claimed
CN-114874362-B Pyridinimine oxime iron catalyst, preparation method thereof and application thereof in conjugated diene polymerization 中国科学院青岛生物能源与过程研究所 2023-05-23 — — CN claimed
WO-2022157656-A1 ANTIVIRAL APPLICATIONS OF PICOLINIC ACID AND ITS DERIVATIVES INDIAN INSTITUTE OF SCIENCE (IN) 2022-07-28 — — WO claimed
US-20220226292-A1 Antiviral Applications of Picolinic Acid and its Derivatives INDIAN INSTITUTE OF SCIENCE (IN) 2022-07-21 — — US claimed
CN-105813478-B Beverage containing ferrous picolinate 雀巢产品有限公司 2019-12-20 — — CN claimed
EP-3086665-B1 FOOD COMPOSITION COMPRISING FERROUS PICOLINATE NESTEC SA (CH) 2017-10-11 — — EP claimed
EP-3086666-B1 BEVERAGE COMPRISING FERROUS PICOLINATE NESTEC SA (CH) 2017-10-11 — — EP claimed
US-20160374370-A1 BEVERAGE COMPRISING FERROUS PICOLINATE NESTEC S.A. (CH) 2016-12-29 — — US claimed
EP-3086666-A1 BEVERAGE COMPRISING FERROUS PICOLINATE Nestec S.A. (CH) 2016-11-02 — — EP claimed
EP-3086665-A1 FOOD COMPOSITION COMPRISING FERROUS PICOLINATE Nestec S.A. (CH) 2016-11-02 — — EP claimed
US-20160309764-A1 FOOD COMPOSITION COMPRISING FERROUS PICOLINATE Société des Produits Nestlé S.A. (CH) 2016-10-27 — — US claimed
WO-2015091093-A1 FOOD COMPOSITION COMPRISING FERROUS PICOLINATE NESTEC S.A. (CH) 2015-06-25 — — WO claimed
WO-2015091092-A1 BEVERAGE COMPRISING FERROUS PICOLINATE NESTEC S.A. (CH) 2015-06-25 — — WO claimed
EP-1411965-A4 METHODS AND COMPOSITIONS FOR CONTROLLING PROTEIN ASSEMBLY OR AGGREGATION NOVACTYL INC (US) 2006-01-11 — — EP claimed
EP-1411965-A1 METHODS AND COMPOSITIONS FOR CONTROLLING PROTEIN ASSEMBLY OR AGGREGATION Novactyl, Inc. (US) 2004-04-28 — — EP claimed
WO-2003006044-A1 METHODS AND COMPOSITIONS FOR CONTROLLING PROTEIN ASSEMBLY OR AGGREGATION NOVACTYL, INC. (US) 2003-01-23 — — WO claimed
US-20020037908-A1 Methods and compositions for controlling protein assembly or aggregation NOVACTYL, INC. 2002-03-28 — — US claimed
US-RE33988-E Dietary supplementation with essential metal picolinates The United States of America as repesented by the Secretary of Agriculture (US) 1992-07-07 — — US claimed
US-4315927-A Dietary supplementation with essential metal picolinates THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) 1982-02-16 — — US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020037908-A1 Methods and compositions for controlling protein assembly or aggregation PSEN1, PSEN2, PRNP CES2 4028/4885CES1 4539/4885L3MBTL1 4530/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.