SCHEMBL6748513

SCHEMBL6748513

CCCC1CCC(C2CCC(C(=O)Oc3cc(F)c(F)c(F)c3)CC2)CC1

nearest known ligand 0.37

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
HTT P42858 2/20 0.36
KMT2A Q03164 2/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
TLR4 O00206 2/20 0.35
F2 P00734 1/20 0.35
CA2 P00918 1/20 0.35
ATM Q13315 1/20 0.34
CYP2C9 P11712 1/20 0.34
ELANE P08246 1/20 0.33
MAPT P10636 2/20 0.33
ALDH1A1 P00352 1/20 0.33
LMNA P02545 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
POLB P06746 1/20 0.32
GAA P10253 1/20 0.32
FFAR4 Q5NUL3 1/20 0.32
KDM4E B2RXH2 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8078007 1.00 HTT (0.36) HTTKMT2ASMN1; SMN2TDP1TLR4
SCHEMBL7521465 1.00 HTT (0.36) HTTKMT2ASMN1; SMN2TDP1TLR4
SCHEMBL8078011 1.00 HTT (0.36) HTTKMT2ASMN1; SMN2TDP1TLR4
SCHEMBL9503498 0.96 KMT2A (0.38) HTTKMT2ASMN1; SMN2TDP1F2
SCHEMBL9764374 0.95 KMT2A (0.37) HTTKMT2ASMN1; SMN2TDP1F2
SCHEMBL12032050 0.94 TLR4 (0.36) HTTKMT2ASMN1; SMN2TDP1TLR4
SCHEMBL12032274 0.94 TLR4 (0.36) HTTKMT2ASMN1; SMN2TDP1TLR4
SCHEMBL8527627 0.93 MAPT (0.40) HTTKMT2ASMN1; SMN2TDP1F2
SCHEMBL8049042 0.93 MAPT (0.40) HTTKMT2ASMN1; SMN2TDP1F2
SCHEMBL8049722 0.91 PKM (0.38) HTTKMT2ASMN1; SMN2TDP1F2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 143 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10457869-B2 Liquid crystal composition and liquid crystal display device JIANGSU HECHENG DISPLAY TECHNOLOGY CO., LTD. (CN) 2019-10-29 US disclosed
US-20180037818-A1 LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JIANGSU HECHENG DISPLAY TECHNOLOGY CO., LTD. (CN) 2018-02-08 US disclosed
US-20170355906-A1 LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY ELEMENT USING SAME DIC CORPORATION (JP) 2017-12-14 US disclosed
US-20170355906-A1 LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY ELEMENT USING SAME DIC CORPORATION (JP) 2017-12-14 US disclosed
US-9828549-B2 Liquid crystal composition, liquid crystal display device, and liquid crystal display DIC CORPORATION (JP) 2017-11-28 US disclosed
US-9828549-B2 Liquid crystal composition, liquid crystal display device, and liquid crystal display DIC CORPORATION (JP) 2017-11-28 US disclosed
US-9822304-B2 Liquid crystal composition and liquid crystal display element containing the same DIC CORPORATION (JP) 2017-11-21 US disclosed
US-9822304-B2 Liquid crystal composition and liquid crystal display element containing the same DIC CORPORATION (JP) 2017-11-21 US disclosed
EP-2891645-B1 PRODUCTION METHOD FOR COMPOUND DAINIPPON INK & CHEMICALS (JP) 2017-10-04 EP disclosed
EP-2801602-B1 NEMATIC LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY ELEMENT USING SAME DAINIPPON INK & CHEMICALS (JP) 2017-10-04 EP disclosed
EP-0733692-B1 Liquid crystalline compound, liquid crystal composition containing the same, and display device CHISSO CORP (JP) 2000-06-14 EP disclosed
EP-0728829-B1 Liquid crystalline alkenylcyclohexene derivative, liquid crystal composition and liquid crystal display element CHISSO CORP (JP) 2000-05-03 EP disclosed
US-6007740-A USED PARTICULARLY TO LOWER THRESHOLD VOLTAGE OF LIQUID CRYSTAL COMPOSITIONS, TO ENLARGE A NEMATIC RANGE, SUCH AS INCREASE IN CLEAR POINT OF LIQUID CRYSTAL COMPOSITIONS AND CONTROL REFRACTIVE ANISOTROPIC VALUE CHISSO CORPORATION (JP) 1999-12-28 US disclosed
EP-0733610-B1 Liquid crystalline compound, liquid crystal composition containing the same and liquid crystal display device CHISSO CORP (JP) 1998-10-28 EP disclosed
EP-0844229-A1 Polyhaloalkyl ether derivatives as well as liquid crystal compositions and liquid crystal display elements containing them CHISSO CORPORATION (JP) 1998-05-27 EP disclosed
CN-1169138-A Novel liquid crystal compound bearing dienyl moiety and liquid crystal composition CHISSO CORP (JP) 1997-12-31 CN disclosed
EP-0805134-A1 NOVEL LIQUID-CRYSTAL COMPOUNDS BEARING DIENYL MOIETY AND LIQUID-CRYSTAL COMPOSITION CHISSO CORPORATION (JP) 1997-11-05 EP disclosed
EP-0733692-A1 Liquid crystalline compound, liquid crystal composition containing the same, and display device Chisso Corporation (JP) 1996-09-25 EP disclosed
EP-0733610-A1 Liquid crystalline compound, liquid crystal composition containing the same and liquid crystal display device Chisso Corporation (JP) 1996-09-25 EP disclosed
EP-0728829-A2 Liquid crystalline alkenylcyclohexene derivative, liquid crystal composition and liquid crystal display element CHISSO CORPORATION (JP) 1996-08-28 EP disclosed