Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 16/20 | 0.58 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.55 |
| ▸ | XDH | P47989 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6748771 | 0.94 | ESR1 (0.51) | ESR1ESR2XDH | |
| Hydrochloric Acid SCHEMBL6749953 | 0.91 | ESR1 (0.52) | ESR1ESR2XDH | |
| SCHEMBL6749914 | 0.88 | BCHE (0.58) | ESR1ESR2 | |
| Hydrochloric Acid SCHEMBL6746980 | 0.84 | ESR1 (0.51) | ESR1ESR2XDH | |
| Hydrochloric Acid SCHEMBL6748793 | 0.83 | ALK (0.51) | ESR1ESR2XDH | |
| Hydrochloric Acid SCHEMBL8592261 | 0.81 | ESR1 (0.55) | ESR1ESR2XDH | |
| SCHEMBL987943 | 0.81 | ESR1 (0.64) | ESR1ESR2 | |
| SCHEMBL6748777 | 0.80 | ESR1 (0.37) | ESR1XDH | |
| Hydrochloric Acid SCHEMBL3974968 | 0.80 | ESR1 (0.64) | ESR1ESR2 | |
| SCHEMBL7118975 | 0.79 | ESR1 (0.54) | ESR1ESR2XDH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6703407-B1 | TREATMENT OF MENOPAUSAL SYNDROME, UTERINE FIBROID DISEASE, ENDOMETRIOSIS, AND AORTAL SMOOTH MUSCLE CELL PROLIFERATION | ELI LILLY AND COMPANY | 2004-03-09 | — | — | US | disclosed |
| EP-0774966-B1 | BENZOFURAN COMPOUNDS, COMPOSITIONS, AND METHODS | LILLY CO ELI (US) | 2003-11-05 | — | — | EP | disclosed |
| EP-0774966-A4 | BENZOFURAN COMPOUNDS, COMPOSITIONS, AND METHODS | LILLY CO ELI (US) | 1998-01-07 | — | — | EP | disclosed |
| EP-0774966-A1 | BENZOFURAN COMPOUNDS, COMPOSITIONS, AND METHODS | ELI LILLY AND COMPANY (US) | 1997-05-28 | — | — | EP | disclosed |
| WO-1996009040-A1 | BENZOFURAN COMPOUNDS, COMPOSITIONS, AND METHODS | ELI LILLY AND COMPANY (US) | 1996-03-28 | — | — | WO | disclosed |