Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4A | O75164 | 1/20 | 0.42 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.42 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 6/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.41 |
| ▸ | CRHBP | P24387 | 1/20 | 0.41 |
| ▸ | TNNT2 | P45379 | 1/20 | 0.41 |
| ▸ | TNNC1 | P63316 | 1/20 | 0.41 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.40 |
| ▸ | CES2 | O00748 | 1/20 | 0.40 |
| ▸ | CES1 | P23141 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL418889 | 0.88 | MAPT (0.47) | MEN1KMT2AL3MBTL1LMNAHTT | |
| SCHEMBL6933067 | 0.81 | POLB (0.40) | MEN1KMT2AL3MBTL1HTTSMN1; SMN2 | |
| SCHEMBL6930354 | 0.81 | POLB (0.46) | MEN1KMT2AL3MBTL1LMNAHTT | |
| SCHEMBL6933157 | 0.77 | GAA (0.46) | MEN1KMT2AL3MBTL1LMNASMN1; SMN2 | |
| SCHEMBL6930693 | 0.77 | GAA (0.55) | MEN1KMT2ASMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL6930285 | 0.75 | SMN1; SMN2 (0.43) | MEN1KMT2ALMNAHTTSMN1; SMN2 | |
| SCHEMBL8489121 | 0.72 | APP (0.43) | MEN1KMT2AL3MBTL1HTTSMN1; SMN2 | |
| SCHEMBL6933815 | 0.72 | RAB9A (0.45) | KMT2ACRHBPCRHR2L3MBTL1HTT | |
| SCHEMBL6748713 | 0.71 | MEN1 (0.47) | KDM4AKDM2AAKR1C3MEN1KMT2A | |
| SCHEMBL6928227 | 0.71 | SMN1; SMN2 (0.43) | MEN1KMT2ALMNAHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6713503-B1 | 1-(2,4-DIMETHYL-PHENYL)-2,4-DIHYDROXY-3-(4-METHYL-BENZOYL)-5-OXO-2,5 -DIHYDRO-1H-PYRROLE-2-CARBOXYLIC ACID METHYL ESTER | UNIVERSITY OF CENTRAL FLORIDA | 2004-03-30 | — | — | US | disclosed |
| US-6713503-B1 | 1-(2,4-DIMETHYL-PHENYL)-2,4-DIHYDROXY-3-(4-METHYL-BENZOYL)-5-OXO-2,5 -DIHYDRO-1H-PYRROLE-2-CARBOXYLIC ACID METHYL ESTER | UNIVERSITY OF CENTRAL FLORIDA | 2004-03-30 | — | — | US | disclosed |
| US-6703426-B1 | 4-(4-CHLORO-PHENYL)-2,4-DIOXO-3- (PHENYL-HYDRAZONO)-BUTYRIC ACID ETHYL ESTER IS ADMINISTERED | UNIVERSITY OF CENTRAL FLORIDA | 2004-03-09 | — | — | US | disclosed |
| US-6703426-B1 | 4-(4-CHLORO-PHENYL)-2,4-DIOXO-3- (PHENYL-HYDRAZONO)-BUTYRIC ACID ETHYL ESTER IS ADMINISTERED | UNIVERSITY OF CENTRAL FLORIDA | 2004-03-09 | — | — | US | disclosed |
| US-6638975-B1 | Treatment of breast cancer | UNIVERSITY OF CENTRAL FLORIDA | 2003-10-28 | — | — | US | disclosed |
| US-6638975-B1 | Treatment of breast cancer | UNIVERSITY OF CENTRAL FLORIDA | 2003-10-28 | — | — | US | disclosed |
| US-6602907-B1 | Treatment of breast cancer | UNIVERSITY OF CENTRAL FLORIDA | 2003-08-05 | — | — | US | disclosed |
| US-6602907-B1 | Treatment of breast cancer | UNIVERSITY OF CENTRAL FLORIDA | 2003-08-05 | — | — | US | disclosed |