SCHEMBL6748982

SCHEMBL6748982

CC(O)c1cccc2nc(C=Cc3nc4ccccc4[nH]3)[nH]c12

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ NPC1 O15118 7/20 0.52
▸ RAB9A P51151 7/20 0.52
▸ ALDH1A1 P00352 7/20 0.52
▸ KDM4E B2RXH2 6/20 0.52
▸ SMN1; SMN2 Q16637 5/20 0.52
▸ MEN1 O00255 5/20 0.52
▸ KMT2A Q03164 5/20 0.52
▸ HPGD P15428 5/20 0.52
▸ PKM P14618 3/20 0.52
▸ HSP90AA1 P07900 1/20 0.52
▸ MAPT P10636 5/20 0.51
▸ LMNA P02545 4/20 0.51
▸ HTT P42858 3/20 0.51
▸ GAA P10253 3/20 0.51
▸ NFKB1 P19838 2/20 0.51
▸ NFKB2 Q00653 2/20 0.51
▸ RELA Q04206 2/20 0.51
▸ TP53 P04637 1/20 0.51
▸ RECQL P46063 1/20 0.51
▸ NPSR1 Q6W5P4 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1086985 0.77 ALDH1A1 (0.81) NPC1RAB9AALDH1A1KDM4ESMN1; SMN2
SCHEMBL1086983 0.77 ALDH1A1 (0.81) NPC1RAB9AALDH1A1KDM4ESMN1; SMN2
SCHEMBL29539476 0.77 ALDH1A1 (0.81) NPC1RAB9AALDH1A1KDM4ESMN1; SMN2
SCHEMBL13479982 0.77 ALDH1A1 (0.57) NPC1RAB9AALDH1A1KDM4ESMN1; SMN2
SCHEMBL11687448 0.72 KMT2A (0.38) KDM4EMEN1KMT2AHPGDLMNA
SCHEMBL17329324 0.72 KMT2A (0.42) ALDH1A1KDM4EMEN1KMT2AGAA
SCHEMBL31305038 0.71 NPC1 (0.89) NPC1RAB9AALDH1A1KDM4ESMN1; SMN2
SCHEMBL29881928 0.71 ALDH1A1 (0.66) NPC1RAB9AALDH1A1KDM4ESMN1; SMN2
SCHEMBL28820772 0.71 ALDH1A1 (0.66) NPC1RAB9AALDH1A1KDM4ESMN1; SMN2
SCHEMBL6598420 0.70 ALDH1A1 (0.65) NPC1RAB9AALDH1A1KDM4ESMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6710024-B2 Washing active preparation BASF AKTIENGESELLSCHAFT (DE) 2004-03-23 — — US disclosed
US-20030109414-A1 Washing active preparation BASF AKTIENGESELLSCHAFT (DE) 2003-06-12 — — US disclosed
EP-0209840-B1 LAYERED SILICATES HAVING A REDUCED SWELLING POWER, PROCESS FOR THEIR PREPARATION AND THEIR USE IN WASHING AND CLEANING AGENTS Henkel Kommanditgesellschaft auf Aktien (DE) 1992-01-02 — — EP disclosed
US-5021182-A N,N,N',N'-Tetraacetylene diamine and pentaacetyl glucose; disinfecting laundry at low washing temperatures Epp, Roman A. (DE) 1991-06-04 — — US disclosed
US-4755319-A Mixing crystallized aluminosilicate moist from production with other ingredients, recovering product HENKEL KOMMANDITGELLSCHAFT AUF AKTIEN (DE) 1988-07-05 — — US disclosed
US-4737306-A MIXED CRYSTAL SYSTEM KENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 1988-04-12 — — US disclosed
EP-0209840-A2 Layered silicates having a reduced swelling power, process for their preparation and their use in washing and cleaning agents Henkel Kommanditgesellschaft auf Aktien (DE) 1987-01-28 — — EP disclosed
EP-0158203-A2 Washing agent Henkel Kommanditgesellschaft auf Aktien (DE) 1985-10-16 — — EP disclosed
US-4396524-A HEATING POLYDIMETHYLSILOXANE AND A POLYSILOXANE WITH AN ACID OR BASIC CATALYST; MIXING WITH SILICA ACID AEROGEL HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 1983-08-02 — — US disclosed
US-4330423-A Process for the production of solid, pourable washing or cleaning agents with a content of a calcium binding silicate HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 1982-05-18 — — US disclosed
US-4110242-A SOLIDS HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 1978-08-29 — — US disclosed
US-4083793-A ETHYLENE OXIDE FATTY ALCOHOL ADDUCT, POLYOXYETHYLENE GLYCOL MODIFIED WITH FATTY ALCOHOL, SODIUM SOAP, SODIUM ALKYLBENZENESULFONATE HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DT) 1978-04-11 — — US disclosed
US-4003841-A Coated stabilized bleach activators, process and washing compositions HENKEL & CIE G.M.B.H. (DT) 1977-01-18 — — US disclosed
US-3985670-A Liquid regulated-foam detergent compositions HENKEL & CIE G.M.B.H. (DT) 1976-10-12 — — US disclosed
US-3975280-A Storage-stable, readily-soluble detergent additives, coating compositions and process HENKEL & CIE G.M.B.H. (DT) 1976-08-17 — — US disclosed
US-3965024-A Washing agent compositions and washing assistant composition containing phosphonopolycarboxylate sequestering agents HENKEL & CIE G.M.B.H. (DT) 1976-06-22 — — US disclosed
US-3962116-A COMPOSITIONS OF OPTICAL BRIGHTNESS AND ALUMINOSILICATES AND METHODS OF THEIR PRODUCTION HENKEL & CIE G.M.B.H. (DT) 1976-06-08 — — US disclosed
US-3954643-A SULFONATE SURFACTANT, FATTY ACID SOAP, BUILDER HENKEL & CIE GMBH (DT) 1976-05-04 — — US disclosed
US-3943178-A WASHING AGENT HENKEL & CIE GMBH (DT) 1976-03-09 — — US disclosed
US-3931033-A ETHOXYLATED ALCOHOL, ALKALI METAL SOAP, SEQUESTERANT, SOLVENT, WATER HENKEL & CIE G.M.B.H. (DT) 1976-01-06 — — US disclosed
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