Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTN3A1 | O00481 | 3/20 | 0.65 |
| ▸ | FNTA | P49354 | 15/20 | 0.50 |
| ▸ | FNTB | P49356 | 13/20 | 0.50 |
| ▸ | PGGT1B | P53609 | 6/20 | 0.50 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Isopentenylpyrophosphate SCHEMBL1981843 | 0.94 | BTN3A1 (0.76) | BTN3A1FNTAFNTBPGGT1BGGPS1 | |
| Isopentenylpyrophosphate SCHEMBL4367209 | 0.94 | BTN3A1 (0.76) | BTN3A1FNTAFNTBPGGT1BGGPS1 | |
| SCHEMBL3211424 | 0.86 | BTN3A1 (0.85) | BTN3A1FNTAFNTBPGGT1BGGPS1 | |
| SCHEMBL3215369 | 0.84 | BTN3A1 (0.81) | BTN3A1FNTAFNTBPGGT1BGGPS1 | |
| SCHEMBL9963967 | 0.84 | BTN3A1 (0.84) | BTN3A1FNTAFNTBPGGT1B | |
| Geranyl Diphosphate SCHEMBL19971954 | 0.84 | FNTA (0.74) | BTN3A1FNTAFNTBPGGT1BGGPS1 | |
| Geranyl Diphosphate SCHEMBL16767264 | 0.84 | FNTA (0.74) | BTN3A1FNTAFNTBPGGT1BGGPS1 | |
| Farnesyl Diphosphate SCHEMBL6061708 | 0.82 | FNTA (0.80) | BTN3A1FNTAFNTBPGGT1BGGPS1 | |
| Isopentenylpyrophosphate SCHEMBL28016670 | 0.82 | FNTA (0.70) | BTN3A1FNTAFNTBPGGT1BGGPS1 | |
| Isopentenylpyrophosphate SCHEMBL16767444 | 0.81 | FNTA (0.78) | BTN3A1FNTAFNTBPGGT1BGGPS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040235797-A1 | Methods for identifying compounds useful for inhibiting farnesyl diphosphate synthase | BERGSTROM JAMES D (US) | 2004-11-25 | — | — | US | disclosed |
| EP-1159447-A4 | METHODS FOR IDENTIFYING COMPOUNDS USEFUL FOR INHIBITING FARNESYL DIPHOSPHATE SYNTHASE | MERCK & CO INC (US) | 2004-11-03 | — | — | EP | disclosed |
| US-20020151459-A1 | Methods for identifying compounds useful for inhibiting farnesyl diphosphate synthase | MERCK & CO., INC. | 2002-10-17 | — | — | US | disclosed |
| EP-1159447-A1 | METHODS FOR IDENTIFYING COMPOUNDS USEFUL FOR INHIBITING FARNESYL DIPHOSPHATE SYNTHASE | Merck & Co., Inc. (US) | 2001-12-05 | — | — | EP | disclosed |
| WO-2000052198-A1 | METHODS FOR IDENTIFYING COMPOUNDS USEFUL FOR INHIBITING FARNESYL DIPHOSPHATE SYNTHASE | MERCK & CO., INC. (US) | 2000-09-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040235797-A1 | Methods for identifying compounds useful for inhibiting farnesyl diphosphate synthase | FDPS, GGPS1, FNTA | BTN3A1 3865/4885FNTA 3/4885FNTB 4/4885 |
| US-20020151459-A1 | Methods for identifying compounds useful for inhibiting farnesyl diphosphate synthase | FDPS, GGPS1, FNTA | BTN3A1 3865/4885FNTA 3/4885FNTB 4/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.